Learn

Physician-reviewed guides to hair loss treatment, backed by clinical evidence.

All 161 guides

Living with hair loss

XYON Patient Success Story: C. D.

XYON user C.D shares his experience using Topical Finasteride with XYON’s SiloxysSystem™ Gel to help with his hair loss.

Science and research

KX-826 (Pyrilutamide) for Hair Loss in 2026

KX-826 (pyrilutamide) is an investigational topical antiandrogen for hair loss. Here’s what 2026 trial data, safety signals, and approval status show.

Complementary care

What to Look for in a Shampoo

Expensive shampoos are not always better. This article breaks down what really drives shampoo cost, which ingredients may be worth paying for, and why shampoo can support scalp health and hair quality without replacing targeted hair loss treatment.

Clinic Spotlight: Shapiro Medical Group in Minneapolis

Shapiro Medical Group stands apart in hair restoration through surgeon-led care, natural-looking results, and a long-term approach to preserving hair. This article explores why their clinical philosophy and surgical reputation make them a strong fit as an XYON Clinic Connect partner.

Science and research

Redensyl for Hair Growth

Redensyl is often marketed as a natural alternative to minoxidil, but the evidence behind it is limited. This guide explains what Redensyl is, whether it can help with hair growth, possible side effects, and why it’s best viewed as a cosmetic add-on rather than a proven treatment for androgenetic alopecia.

XYON Patient Success Story: Freddy

We’re proud to share success stories from real patients navigating hair loss in different ways, because no two journeys look exactly the same. Freddy, who started on our topical...

Science and research

PP405 for Hair Loss – The Complete Guide 2026

PP405 is a novel topical hair loss treatment being developed by Pelage Pharmaceuticals that can potentially help stop hair loss and regrow hair for men experiencing androgenetic alopecia (AGA). This article provides an overview of what PP405 is, where the research is at, and what options are readily available now to help with hair loss.

Clinic Spotlight: Sara Wasserbauer, MD (California Hair Surgeon)

Effective hair restoration doesn’t begin with picking between how the donor hairs are harvested. It begins with the surgeon’s judgment and their plan to get the results their patients ca be proud of. It’s about how they assess patient risk for future thinning, how they protect a limited donor supply, and how they design a hairline that actually suits facial structures. It is not about planning what hair will look like next year, but what it will look like a decade from now. That mindset is exactly what defines Dr. Sara Wasserbauer’s practice and why we’re proud to spotlight her clinic this month.

Science and research

RU58841 for Hair Loss

RU58841 is a non-steroidal anti-androgen that has gained attention in hair loss communities as a potential alternative to topical finasteride. Does it work, is it safe and how does it compare with finasteride? Currently, there aren’t definitive answers to these questions, but this article is here to help separate fact from fiction.

Finasteride

Topical Finasteride in Canada: 2026 Guide

Topical finasteride is emerging as an option for Canadians who want finasteride’s hair-saving benefits but worry about systemic side effects. This 2026 guide breaks down how it works, reviews the clinical evidence, and how topical finasteride can be accessed in Canada. It also includes information that Canadians should know before using it.

Science of hair

How To Prepare for a Hair Transplant

A hair transplant is a commonly performed procedure and in the right hands, is generally a low risk surgery. Outcomes can depend heavily on the quality and experience of the surgeon, but there are steps that patients can take to prepare well ahead of time. With proper planning, it's possible to greatly improve the chances of having a successful hair transplant that looks great and lasts for as long as possible.

Partner Spotlight: Unger Medical (NYC)

Unger Medical is a boutique, surgeon-led hair restoration clinic on Park Avenue in New York City, known for meticulous planning, natural-looking results, and a one-patient-per-day focus. This approach allows Dr. Robin Unger to focus fully on the details that separate an average result from an exceptional one.

Complementary care

7 Dermatologist Recommended Hair Growth Products

With so many options to choose from, it can be hard to know which hair loss solutions and products actually work. This article rounds up the top 7 hair growth solutions and products for the scalp and hair, fact-checked by a board-certified dermatologist for a stress-free hair regrowth journey.

Causes of hair loss

Diffuse Thinning: What It Is, Why It Happens, and the Best Treatments

Diffuse thinning is characterized by hair loss all over the scalp rather than a specific bald spot. While often mistaken for standard male pattern baldness, it can be caused by a variety of other factors including other genetic predispositions. Learn how to identify the signs, understand the triggers, and explore options for treatment.

Causes of hair loss

Weight Loss & Hair Loss: Why Does it Happen?

Hair loss is a well-known potential side effect of weight loss, especially if weight loss happens quickly over a short period of time. With the popularity of weight loss medications such as GLP-1s, more patients are noticing thinning hair. This article examines more closely the relationship between weight loss and hair loss and what to do if patients are noticing increased shedding while trying to lose weight.

Partner Spotlight: Anti Aging Vancouver

Anti-Aging Vancouver stands out for its comprehensive balance of physician-lead cosmetic treatments that blend medical expertise with aesthetic artistry. They offer hormone optimization for men and women, comprehensive menopause and andropause management, sexual wellness treatments, regenerative therapies including PRP and exosomes, and advanced hair restoration options which include XYON’s suite of hair loss solutions.

Causes of hair loss

Does Phentermine Cause Hair Loss?

Phentermine can trigger temporary hair shedding, usually from rapid weight loss, nutrient deficiency, or metabolic and hormonal stress. It may also “unmask” underlying genetic hair loss. This article explains how to tell what’s causing shedding, how long it typically lasts, and what can be done to manage hair loss and regain hair density.

Finasteride

Does Finasteride Work?

Finasteride remains the gold-standard treatment for male pattern baldness, but results vary by person. This article offers a refresher on how it works, who is most likely to benefit, how long it takes to see results. Also included are examples of real patient results to help support the clinical findings.

Partner Spotlight: Anderson Center for Hair

Modern hair transplants can look so natural that even close inspection won’t reveal surgery. In this month’s Partner Spotlight, we're featuring Dr. Ken Anderson of Anderson Center for Hair in Atlanta, an early FUE pioneer known for surgeon-led procedures, undetectable donor work, and natural hairline design, supported by long-term medical hair-loss planning.

Causes of hair loss

How to Prevent Hair Loss

Hair loss can be slowed down or even prevented if it is correctly identified and treated early. This article provides a high-level overview of the most common kinds of hair loss affecting men and rounds up the top 8 dermatologist-vetted tips for how to get ahead of hair loss.

Minoxidil

Does Minoxidil Work for a Receding Hairline?

Minoxidil can help restore the look of a receding hairline, but the key is catching signs of thinning early and staying consistent with treatment. This article dives deeper into the history of minoxidil, the evidence that supports its efficacy for pattern hair loss, how to use conventional forms of topical minoxidil, and safety considerations.

XYON Health Partner Spotlight: Hasson & Wong

Dr. Hasson and Dr. Wong have earned an unmatched reputation for delivering natural looking hair transplants spanning decades. With hundreds of authentic before-and-after photos and unretouched videos, they have proof that you can trust them to deliver the best results possible.

Living with hair loss

How to Boost Confidence While Coping with Hair Loss

The feelings that come with noticing hair loss can be uncomfortable and hard to talk about, but there are practical things that patients can do to help boost confidence and manage some of the negative emotions that can come with thinning hair. This article examines the psychosocial effects of hair loss and offers a step-by-step guide to building back confidence.

How To Maintain Sexual Health

Men’s sexual health is core to overall wellbeing, not just bedroom performance. This piece by Dr. Simon Pimstone covers benefits of sex, common issues like ED and low libido, ev...

Partner Spotlight: Trichogenics, Hair Transplants in Greece & Israel

For those comparing transplants in the world, whether looking at clinics in Turkey, the United States, or elsewhere, Trichogenics offers a unique balance: expert hair transplant surgeons, state of the art methods, and trusted follow-up care. Trichogenics is led by American board-certified doctors who personally perform every transplant. The clinic focuses only on FUE (Follicular Unit Extraction) and DHI (Direct Hair Implantation), ensuring minimally invasive, natural results.

Finasteride

How Finasteride Affects Male Fertility

Pattern hair loss doesn’t only affect older men. In fact, it can strike at any point after you hit puberty and the specific timing has a lot to do with genetics, especially if a male family member also has hair loss. This means that many men find themselves dealing with hair loss while they’re considering starting a family. This article helps answer some of the most common questions about finasteride and male fertility, including whether it’s safe to use if patients are planning to have a baby or if a partner is currently pregnant.

Minoxidil

Before and After Using Oral Minoxidil

Oral minoxidil is increasing in popularity as a potential off-label solution for patients experiencing pattern hair loss. It can be prescribed in a low-dose format which may help reduce the risk for possible systemic side effects. This article answers frequently asked questions about what to expect when taking oral minoxidil, including safety and efficacy considerations and who oral minoxidil may be right for.

XYON Health Clinic Connect Partner Spotlight: Dr. Ross Kopelman, Leading Hair Transplant Surgeon in NYC

In our inaugural clinic spotlight, we take a closer look at Dr. Kopelman and his clinic, while providing an overview of NYC hair transplant costs, procedures, and patient experiences so you can make an informed decision when deciding on who you want to perform your hair transplant.

Sildenafil Vs Viagra: Which Is Better?

With the wide availability of generic medications, many patients are wondering if there are any difference between generic sildenafil and Viagra. Is one better than the other? A...

Tadalafil for Body Building and Muscle Growth

Tadalafil is commonly used to treat ED, but has been gaining attention as a potential muscle growth aid. It's not currently FDA-approved for muscle growth or performance enhance...

Complementary care

Tea Tree Oil for Hair: The Complete Guide

Tea tree oil has been used for centuries as a natural treatment for scalp and hair health. It is purported to help with flakes and itchiness, and prevent buildup from hair products. This article covers what tea tree oil is used for, how to use and incorporate it into a hair care routine, and safety considerations.

Science and research

What Is Breezula® (Clascoterone)?

Breezula® (clascoterone) is a promising topical antiandrogen currently in late-stage clinical trials for treating hair loss. Unlike finasteride, which lowers DHT levels systemically, Breezula works by blocking DHT from binding to androgen receptors in the scalp, potentially offering a safer option for those concerned about systemic side effects. This article provides a summary of currently available clinical evidence, how it compares to other medications, and what to do while waiting for its approval.

Best Medication for Erectile Dysfunction Without Side Effects

Erectile dysfunction is more common than most people think. Fortunately, there’s a whole class of medications called phosphodiesterase type 5 inhibitors (PDE5is) that can be use...

What’s the Right Sildenafil Dosage for Erectile Dysfunction?

The proper dosage for sildenafil (Viagra) will vary between 25mg and 100mg once daily, with the most prescribed dosage being 50mg. Patients generally start with a lower dosage o...

Finasteride

Is Finasteride Safe?

Finasteride is by far the most prescribed hair loss medication for men, but is it safe? With compounded and non FDA approved forms of finasteride on the rise and an increase in reports of potential long-term side effects, it makes sense that patients want the facts. This article covers everything you need to know about whether finasteride is still safe to take and provides tips for how to make the most of treatment while prioritizing patient safety.

Tadalafil Dosage Guide

Along with sildenafil, tadalafil is a medication commonly prescribed for erectile dysfunction. It’s available in several different dosage strengths and two different dosing regi...

Complementary care

Building an Effective Men's Haircare Routine

Board-certified dermatologist and Medical Director at XYON, Dr. Christina Han, helps cut through the noise around building an optimal hair care routine and selecting products that actually work. In this guide, she offers practical tips for creating a streamlined and scientifically backed hair care routine that works for you.

Finasteride

Is Topical Finasteride FDA-Approved?

In April 2025, the FDA released a warning to physicians, compounding pharmacies, and consumers about potential risks associated with the use of topical finasteride. This article offers additional information for readers who may be considering topical finasteride treatments through XYON, or current patients who may have questions about the safety of these compounded treatments.

Causes of hair loss

How to Stop Hair Loss from Antidepressants

Globally the number of people taking antidepressants is rising, but like most medications, there are possible side effects. One that's gained attention recently is hair loss. While a direct causal link hasn't been established, there are concerns that hair loss could exacerbate existing mental health challenges or force a decision to be made between treatments. This article explores the possible link between antidepressant use and hair loss, whether this hair loss is permanent, and what can be done about it.

Dutasteride

How to Avoid Erectile Dysfunction on Dutasteride for Hair Loss

The safety profile of dutasteride is believed to be similar to finasteride and erectile dysfunction is a known risk for both medications. Side effects are possible with any medication, though this risk can be lowered. This article takes a closer look at the mechanism of dutasteride, the risk for erectile dysfunction and how this can be minimized, and the question of whether permanent sexual side effects are also an issue with this medication.

Causes of hair loss

Does Creatine Cause Hair Loss?

Creatine is a commonly used as a pre-workout supplement because of its ability to improve muscle endurance and energy. Recently, there has been speculation online that creatine could contribute to hair loss. But how much evidence is there to support the theory that creatine actually causes thinning? This article take a closer look at this issue and sets the record straight on whether creatine should be avoided.

Finasteride

Topical Finasteride vs. Oral Finasteride

As topical finasteride grows in popularity, it is important to understand the benefits and possible risks of oral vs topical treatment options. This article covers essential information on the differences between these formats, including answers to two big questions: is one stronger, or more effective than the other, and is there a difference in side effects?

Finasteride

Topical Finasteride and Erectile Dysfunction

Finasteride is typically prescribed as an oral tablet taken once a day, but other forms of finasteride also exist. For patients worried about potential sexual side effects like erectile dysfunction (ED), topical finasteride could be an option. Data from preliminary studies shows that it may be as effective as oral medication, with a lower risk of systemic side effects. This article examines the clinical evidence for its efficacy and whether it can help lower the risk for ED.

Science and research

Sexual Side Effects of Finasteride

Many men can take finasteride without any problems, but numerous studies have shown that finasteride can cause sexual side effects in some patients. This article takes a closer look at the most common sexual side effects associated with taking finasteride, how frequently they occur and importantly, how patients might be able to minimize this risk.

Pattern hair loss basics

Using Finasteride After A Hair Transplant

For some hair loss patients, the best treatment option is a surgical hair transplant. Contrary to popular belief, pharmacological management may be necessary both leading up to, and after a successful hair transplant to maintain results. This article reviews the reasons for starting or continuing to take finasteride after a hair transplant and how it can affect the success of a hair restoration procedure.

Complementary care

Does Red Light Therapy Work for Hair Loss?

Red light therapy is a type of photo biomodulation. Photo biomodulation involves using light, which is a form of energy, to stimulate biological processes such as hair growth and collagen production. This article examines what it is, how it's used to promote hair loss, the current clinical evidence, and whether it can be combined with other adjunctive therapies.

Pattern hair loss basics

Can Hair Grow Back After Balding?

Can hair grow back after going bald and is there anything that can be done to stop it from progressing? The answer depends on the cause of hair loss and how advanced it is. In general, prevention is key and once hair is fully gone it usually does not grow back. However, there are situations where regrowth is possible if hair loss is identified early. This article breaks down which types of hair loss can grow back and which treatments can help, and provides tips to prevent it from getting worse.

Complementary care

Best Oils for Hair Growth

Essential oils have been used for centuries in hair care to promote growth, improve scalp health, and enhance texture. Before incorporating essential oils into a hair care routine, start with understanding the difference between various oils, what aspects of hair growth they target, and why its important to be realistic about what they can do for hair.

Finasteride

Finasteride vs Dutasteride

Finasteride and dutasteride are 5-alpha reductase inhibitors commonly used in the management of male pattern hair loss. This article provides an overview of key differences in cost, safety, and efficacy, and offers general guidance on how to decide between these options.

Science of hair

What is a trichologist?

Trichology is the para-medical study of hair, hair loss and scalp related problems. Trichologists typically utilize a more holistic approach to treating hair and scalp concerns. This article discusses what a trichologist does, how they can help with hair and scalp concerns, and when it may be necessary to see one.

Causes of hair loss

Steroids and Hair Loss

Steroids are synthetic forms of male sex steroid hormones, most commonly testosterone, that may be used by athletes and non-athletes to increase muscle mass and improve athletic and physical performance. These performance enhancing substances can mimic the effects of male sex steroid hormones, leading to speculation that they can cause hair loss in some men. This article explores this issue in depth with insight from a licensed dermatologist.

Science of hair

Scalp Inflammation and Hair Loss

Hair loss is a complex and often multi-factorial condition that nearly 80% of men will experience in their lifetime, yet there are many processes relating to hair loss that we still don’t fully understand. One of these is scalp inflammation. This article examines the relationship between scalp inflammation and hair health, the impact of hair loss treatments on scalp health, and tips for how to maintain scalp health while also managing hair loss.

Finasteride

Does Finasteride Affect Muscle Growth?

Since finasteride interacts with male hormones, concerns have grown around how the drug may impact muscle growth and hinder muscle development. This article examines the research that exists on finasteride's role in muscle anabolism and catabolism and whether there is a real safety risk.

Complementary care

Natural DHT Blockers

To slow or prevent male pattern balding, naturally occurring DHT-blocking agents and products containing DHT-blocking ingredients can be considered. This article explores several of these ingredients and reviews the relevant research surrounding them. Included are expert insights from Dr. Christina Han, a board-certified dermatologist and XYON’s Medical Director, on whether these natural ingredients are truly beneficial for hair growth and they can be used alongside prescribed medication for hair loss.

Finasteride

Finasteride Results

The timeline of hair regrowth or halting hair loss on finasteride can vary from person to person, making it difficult to provide exact timeframes for what to expect. However, patients are generally advised to stay on treatment consistently for at least 6 months before evaluating efficacy. This article provides general guidance for what to expect in the first few months to first year of starting finasteride.

Dutasteride

Dutasteride Dosage

Dutasteride is most commonly prescribed off-label for hair loss at an oral dose of 0.5mg per day, but may also be prescribed at lower doses such as 0.125mg or 0.25mg, depending on the patient. It can also be prescribed off-label for hair loss in topical form, but the ideal dose or concentration for a topical formulation is less cut-and-dry. This article discusses dosage considerations for dutasteride and how format can affect dose, with topical dutasteride from XYON as an example.

Minoxidil

Minoxidil Dosage

Minoxidil is increasingly being prescribed off-label as an oral medication to help with thinning hair. This article discusses the various dosing options for oral minoxidil, what low-dose minoxidil is, and why XYON offers compounded oral minoxidil tablets that also contain Vitamin D.

Dutasteride

The Importance of Dutasteride Treatment Adherence

Treatment compliance is an important factor that can affect the effectiveness of pharmacological interventions. For hair loss, this is especially important because pattern hair loss is a progressive condition that requires sustained suppression of DHT levels to be effective. This article includes expert insights from a licensed dermatologist about the importance of consistency when on dutasteride treatment and what to do if patients miss a dose.

Finasteride

Finasteride Dosage Explained

Finasteride belongs to the class of drugs known as 5-alpha reductase inhibitors. Its role is to prevent testosterone from being converted into DHT, which in turn lowers DHT levels at the scalp to help prevent hair follicle shrinkage. Many patients have questions about dosing for finasteride, particularly with the more recent availability of compounded topical formulations that are not standardized. This article discusses approved and non-approved doses of finasteride and related safety considerations.

Complementary care

Is Dimethicone Bad For Hair?

Dimethicone is a type of silicone commonly used in skincare and hair care products to improve the texture of formulas, giving them a silkier and smoother feel. It can also protect hair against damaging processes, such as hair dyes and exposure to UV, and help retain hair's moisture. This article takes a closer look at why dimethicone is included in formulas, its effect on hair and hair health, and whether it can be damaging to hair.

Causes of hair loss

Why Does Chemotherapy Cause Hair Loss?

Chemotherapy drugs target and destroy rapidly multiplying cancer cells, but they can also damage healthy cells in the body, including hair cells. An estimated 65% of people experience hair loss with this treatment. This article discusses why hair loss can occur with chemotherapy, whether the effects are permanent, and methods to prevent or mitigate the effects.

Causes of hair loss

What Medications Cause Hair Loss?

This article focuses on four types of common medications that have been associated with hair loss and considers the possible mechanisms behind these links. These medications include blood pressure medications, acne medication, NSAIDs, and oral contraceptives. Ultimately, patients are encouraged to discuss possible drug interactions and the risk of hair loss associated with any medications they are taking with their doctor.

Causes of hair loss

Could Stress Cause Hair Loss?

Stress is a known contributor to many types of hair loss, including telogen effluvium, trichotillomania, alopecia areata and post-partum hair loss. Stress can cause hormonal imbalances or trigger an autoimmune response that can lead to hair growth cycle dysregulation, or prompt destructive behaviours like hair pulling. This article discusses the differences between different kinds of stress-related hair loss, distinguish it from other types of hair loss, and provides recommendations for how to manage it.

Finasteride

Does Topical Finasteride from XYON Contain Alcohol?

Many patients opting for topical treatment of pattern hair loss have concerns about the risk for skin irritation and dryness commonly associated with alcohol-based excipients. This article provides an overview of some of the more common ingredients known to trigger skin sensitivities and answers questions about the ingredients in XYON's own gel base.

Finasteride

Does Finasteride Cause Depression?

In 2019, revisions were made to the drug monograph for oral finasteride by the FDA and Health Canada to add depression to the list of potential side effects associated with the medication. This article takes a closer look at the possible relationship between 5-ARIs and mental health and whether topical formulations may be able to lower this risk.

Complementary care

Growth Factors in Hair Serum

Growth factors are fragments of proteins naturally occurring in all cells around the body that facilitate cell-to-cell communication and influence cell behaviour. Increasingly, they are being used in cosmetics including hair care products. This article dives into VEGF and FGF, their role in hair growth, and the clinical evidence that surrounds them.

Causes of hair loss

UV Hair And Scalp Protection

There are several benefits to properly protecting the scalp and hair from UV exposure, including minimizing the risk for skin cancers and maintaining soft and healthy hair. This article examines more closely the effect of UV exposure on the scalp and hair offers recommendations for how to mitigate damage. Dr. Christina Han, a licensed dermatologist, also gives her expert advice on sun protection for the hair and scalp.

Finasteride

The Advantages of Using Minoxidil While Taking Finasteride

Growing clinical evidence suggests that treatment with a combination of finasteride and minoxidil can optimize pattern hair loss results. This article provides an overview of how these agents work independently, the literature that supports their use at the same time, considerations for safety, and ways to incorporate a second agent into an existing treatment regimen.

Causes of hair loss

Caffeine and Hair Loss

Caffeine is theorized to play a role in hair growth. Some research has suggested it may have DHT-blocking properties and prolong the anagen (active growth) phase of the hair growth cycle. This article reviews the role of caffeine in hair growth, differences between ingested and topically-applied caffeine, and whether it should be included in a hair care routine.

Pattern hair loss basics

When Is the Best Time to Start Hair Loss Treatment?

Pattern hair loss is a progressive condition and earlier intervention is typically recommended for an optimal treatment response. This article covers some frequently asked questions about the best time to start treatment, signs to look out for, and whether there is a link between timing hair loss intervention and treatment success.

Complementary care

Using Ketoconazole and DHT Blocking Shampoo For Hair Loss

Ketoconazole is a common ingredient added to shampoo formulas intended to treat and manage dandruff. More recently, it's been recognized as potentially useful adjunct for hair loss, owing to its anti-inflammatory and potentially DHT-blocking properties. This article discusses the clinical evidence for ketoconazole in hair loss treatment, how it compares to other DHT-blocking agents, and whether these can be used together.

Complementary care

Hair Oil vs Hair Serum: Which is Better?

Hair serums and hair oils can be useful tools when it comes to achieving hair goals. Hair serums can offer both short-term and long-term benefits, while oils are typically chosen for their ability to immediately improve the look and feel of hair. In some cases, there is room for both categories of products in a hair routine. This article considers the differences between these options and how to integrate them into a routine.

Minoxidil

Does Rogaine Work?

Rogaine® is the brand name for topical minoxidil. The FDA and Health Canada have approved Rogaine® for the treatment for pattern hair loss in men and women as either a solution or foam at concentrations of 2% and 5%. This article summarizes the clinical evidence supporting this form of minoxidil and addresses questions about whether different scalp areas respond differently to treatment.

Complementary care

Microneedling For Hair Loss: Do You Need It?

Microneedling is a minimally invasive procedure that typically involves using a pen-like device containing needles between 0.5mm and 1.5mm long to create ‘micro-wounds’ in the skin to promote wound healing mechanisms that are believed to contribute to hair growth. This article discusses the current clinical evidence for microneedling, as well as the potential benefits and risks.

Complementary care

Vitamin D and Hair Loss

Vitamin D is believed to have some involvement in regulating the hair growth cycle and specifically, the activity of cells called keratinocytes. It is also one of the vitamins most commonly implicated in hair loss disorders such as alopecia areata. This article discusses the link between Vitamin D deficiency and hair loss, its role in the hair growth cycle, and how much Vitamin D is needed to maintain optimal hair health.

Genetics and Male Pattern Hair Loss: An Interview with Dr. Jerry Cooley

Dr. Simon Pimstone is joined by Dr. Jerry Cooley, a pioneer in the field of surgical hair transplantation and lead surgeon at the Cooley Hair Centre for a conversation around the latest research and guidance on the causes and treatment of hair loss, as well as a deep dive into the complex relationship between DHT and thinning.

Finasteride

How to Make Topical Finasteride

The popularity of topical finasteride as a format may be driving an increase in at-home compounding of topical finasteride. While the process seems straightforward, doing so introduces several risks, including the inability to accurately control dosing and concentration. This article does into detail about why compounding topical finasteride is not recommended and alternatives to consider.

Finasteride

Microdosing Finasteride: What Is It? Does It Work?

Microdosing finasteride or microdosing dutasteride is a practices that involves the patient splitting, cutting, or otherwise diluting their medication so that they receive a smaller “micro” dose of the treatment each time it is taken. It is generally not a recommended practice, as it introduces variables that may affect efficacy and importantly, safety. This article covers what microdosing of 5-ARIs is, the rationale behind it, and potential pitfalls.

Pattern hair loss basics

Treatment Adherence: The Secret to Great Hair Regrowth Results

Dr. Christina Han, a board-certified dermatologist and Medical Director at XYON explains why it’s so important to follow the treatment plans recommended by prescribing physicians if the goal is to optimize treatment response and mitigate safety risks.

Living with hair loss

How Hair Loss Affects Low Self-Confidence in Men

Research has shown that men and women can be equally affected by social media and feel similar pressures to uphold standards for physical appearance. For men in particular, loss of hair signifies a loss of youth or aging with potentially serious effects on self-confidence and self-perception. This article includes a high level overview of current research on confidence and hair loss in men and provides strategies for how to manage and improve self confidence.

Living with hair loss

Feeling Depressed About Going Bald?

Feeling depressed about going bald is not uncommon and it is nothing to be ashamed of. Losing your hair can often equate to a loss of self-confidence and self-esteem, but it is important to acknowledge these feelings and seek help if possible. This article unpacks the psychological impact of hair loss and its connection to depression and anxiety, and provides some guidance on how to approach these complex issues.

Science of hair

Does My Hair Type Put Me at Risk For Hair Loss?

This article offers a concise guide to different hair types, impact of texture and porosity on hair appearance and health, and general care tips based on hair type. The influence of gender and ethnicity on hair loss risk are also discussed.

Complementary care

Will Rice Water Grow Your Hair?

Rice water has gained popularity in online circles as yet another natural remedy for hair loss. The practice of using rice water for hair growth has its roots in Asian cultural traditions and there is some literature that points to the presence of beneficial compounds such as inositol and other antioxidants. This article discusses whether rice water should be included in a hair care routine and summarizes the potential benefits and risks.

Causes of hair loss

HRT and Hair Loss

HRT is a common and effective solution to managing symptoms of menopause, however, there are concerns around whether it may increase the risk for female pattern hair loss. This article reviews the current clinical evidence for HRT and hair loss and provides general guidance on how to prevent hair loss during this challenging life stage.

Causes of hair loss

Is My Hairline Mature or Receding?

Noticing changes in your hairline may be an early sign of a receding hairline, and androgenetic alopecia may be the cause. The good news is, there are many effective treatment options available, but early intervention is key. This article helps differentiate a mature hairline from a receding one and provides recommendations for how to retain hair here.

Spironolactone

Does Spironolactone Cause Weight Gain?

Spironolactone can be a helpful medication for a variety of conditions ranging from heart failure to female pattern hair loss as a result of PCOS. But can spironolactone cause weight gain? This article explores the factors that could be contributing to the link between spironolactone and weight gain.

Complementary care

Essential Oils for Hair Growth

Essential oils are extracted from plants and used for a variety of alternative medicinal and cosmetic purposes. However, essential oils and hair oils specifically formulated for hair are fundamentally different products. The latter provide a more specialized approach to hair health concerns with fewer safety risks. This article discusses several common essential oils used in hair and skin applications, including rosemary, peppermint, lavender, and lemongrass oil.

Living with hair loss

Would You Talk to Your Mom About Hair Loss? An Interview with Dr. Christina Han, MD

In this exclusive editorial, Dr. Christina Han, a board-certified dermatologist and Medical Director at XYON, joins us for a heart-to-heart conversation about the role that her mother has played in her life and what advice she would give to her own daughters on navigating health changes like hair loss.

Pattern hair loss basics

What Are DHT Blockers and How Do They Affect Hair Loss?

DHT blockers are also known as 5-alpha reductase inhibitors (5-ARIs). Their mechanism of action is to block the conversion of testosterone into DHT, making them a potentially helpful tool in the management of androgenetic alopecia. The two best known examples of DHT blocking medications in North America are finasteride and dutasteride. This article addresses common questions around what DHT blockers are, how they work, and clinical evidence around safety and efficacy.

Causes of hair loss

Does Ozempic Cause Hair Loss?

With the skyrocketing popularity of GLP-1s such as semaglutide (Ozempic) there have also been increasing reports of hair loss as a side effect. It is well-established that sudden and significant weight loss can affect hair growth. This article explores whether there is a causal relationship between Ozempic and hair loss, and potential explanations for hair loss that go beyond use of these medications.

Causes of hair loss

Do Hats Cause Hair Loss?

Hats are often worn by those with thinning hair to hide hair loss, but could they also be responsible for hair loss? This article explores common myths and concerns about hat wearing and thinning, why hats may actually be beneficial, and recommendations for how to maintain a healthy scalp in this exclusive interview with Dr. Christina Han, a licensed dermatologist.

Complementary care

Can Conditioner Cause Hair Loss?

Conditioner is a product that many people use as part of their haircare routines, but can it cause hair loss? This article features an exclusive interview with licensed dermatologist Dr. Christina Han where she debunks several myths surrounding conditioner and hair loss and explains the benefits of using conditioner.

Complementary care

Does Biotin Help Hair Growth?

Biotin is present in many foods including eggs and nuts and is commonly included in supplements targeting hair and skin health. This article delves deeper into topics such as the debate around whether it actually benefits hair growth, dosing, and safety precautions.

Complementary care

Does Collagen Help Hair Growth?

Collagen has been shown to play a role in hair growth cycle dynamics and supporting the normal development of hair and skin cells. However, there is a paucity of evidence around collagen's benefits, particularly when taken orally. This article examines these potential benefits and risks in more detail, identifies who is most likely to benefit from taking collagen, and whether it's sufficient as a hair loss therapy.

Causes of hair loss

Menopause and Hair Loss

For many women, menopause is a significant life event. It involves biological changes that mark the end of the reproductive years, but also carries its own emotional and psychological weight. One "symptom" of menopause is hair loss. In this article, we want to shed light on what causes hair loss during menopause, the relationship between hormone levels and the hair growth cycle and how menopause hair loss can be treated.

Pattern hair loss basics

Is Female Pattern Hair Loss Reversible?

Although it’s less common than male pattern hair loss, female pattern hair loss is the most common type of hair loss among women. Evidence suggests that DHT may play a role in the development of FPHL, but it is not the primary causal factor. Knowing this, should women be concerned about the effectiveness of agents like finasteride in the treatment of female pattern hair loss? Is female pattern hair loss reversible? This article provides an overview of differences between male and female hair loss and discusses whether a different approach may be needed for female hair loss.

Living with hair loss

3 Ways to Support Your Partner with Hair Loss

Talking to a significant other about a change in their appearance can be difficult, however, there are ways to approach this conversation that prioritize the emotional safety and wellbeing of the affected partner. This guide delves deeper into the psychosocial effects and real mental health consequences of hair loss, and offers suggestions for how to talk to a loved one about this common problem.

Complementary care

Hair Thickening Shampoos: Do They Work? Q&A with Dr. Han

Hair thickening shampoos can include ingredients that plump and add volume to hair strands and ingredients that offer DHT-blocking benefits. The latter can be useful for individuals suffering from progressive thinning. This article provides a refresher on what causes hair loss, sheds light on what ingredients to look for, and how to incorporate hair thickening shampoos into a haircare routine.

Spironolactone

Spironolactone for PCOS

Spironolactone is often prescribed off-label to help manage symptoms of PCOS. The medication works by modifying the body’s response to male sex steroid hormones, which in some women can cause excessive body hair growth, acne and even pattern hair loss. Read on to find out how spironolactone works, possible risks, and who it may be right for.

Finasteride

Finasteride and Prostate Health

For as long as finasteride has been approved for the treatment of male androgenetic alopecia and benign prostatic hyperplasia, there have been questions raised about its effects on male reproductive and prostate health. This article examines finasteride use and its potential effects on prostate health and in particular, prostate cance risk.

Minoxidil

Minoxidil for Beard Growth

Minoxidil is commonly used to combat hair loss on the scalp, but many wonder whether it can also be used as a hair growth aid for other parts of he body. This article examines whether minoxidil can and should be used for beard growth, safety considerations and alternatives for boosting facial hair growth.

Minoxidil

How To Use Minoxidil

Minoxidil is available in topical and oral forms (off-label) and is an important treatment option for men and women experiencing pattern hair loss. This article provides general usage guidelines for both of these formats and summarizes some key safety considerations. Patients are encouraged to talk to their doctor about specific concerns or deviations from recommended dosing.

Spironolactone

Spironolactone for Hair Loss

Spironolactone is type of medication called an anti-androgen that can be prescribed off-label to help with thinning hair. It works by blocking the effects of androgens like DHT. Data from small clinical and case studies suggests that it may be an important treatment option for women suffering from pattern hair loss, with many patients reporting successful halting of the progression of hair loss and hair regrowth.

Finasteride

Using Finasteride and Minoxidil Together

Stopping hair loss and regrowing hair is a complex, coordinated process that sometimes warrants the use of more than one pharmacological agent. Finasteride and minoxidil are some of the most well-studied medications for hair loss and data shows that using these two agents together can produce significantly better clinical outcomes than either of these treatments on their own. This article takes a closer look at the data that exists to support the combination of using finasteride and minoxidil, the best way to take these treatments together, and possible side effects.

Causes of hair loss

Causes of Hair Loss in Women

Hair loss in women is a complex health issue that can have a multitude of causes and triggers. The goal of this article is to provide an overview of the most common causes of hair loss in women based on life stage, guidance on how different types of hair loss can be identified and differentiated, and strategies for prevention and management.

Complementary care

Vitamins and Hair Loss

Vitamins are micronutrients that participate in normal cell growth and development and supporting the immune system. In some cases, they also play specialized roles in the maintenance of healthy hair. Vitamins D, B7 (biotin), C and iron have been shown to influence hair growth cycle dynamics, impact hair strength and structure, and provide antioxidant support. This article discusses the evidence around these vitamins, who they are best for, and provides some recommendations for how to incorporate them into a hair care routine.

Causes of hair loss

Pregnancy and Hair Loss

Post pregnancy hair loss (or postpartum hair loss) refers to the sudden and often dramatic shedding that starts approximately 2-4 months after giving birth. Experts believe may be caused by dramatic hormonal changes occurring in the body during and immediately after pregnancy and delivery. This article takes a closer look at hair loss associated with pregnancy and delivery, how this differs from other types of hair loss, and whether it requires intervention.

Causes of hair loss

PCOS Hair Loss

PCOS is an example of an endocrine disorder and involves the ovaries, which are normally responsible for secreting sex hormones critical to regulating reproduction. Women who produce excess androgens because of PCOS can experience a variety of signs and symptoms, including both excess facial and body hair growth and hair loss. This article takes a closer look at the effects of PCOS on hair growth, whether PCOS related hair loss can be treated, and options for treatment.

Spironolactone

Spironolactone Side Effects

Spironolactone may be prescribed off-label to manage a variety of medical conditions including pattern hair loss in women, adult acne, hirsutism (excess body hair growth) and polycystic ovarian syndrome (PCOS). While it can be effective, there are possible risks and side effects that you should be aware of. This article summarizes some of the most common side effects of spironolactone and delves into special safety considerations for female patients.

Finasteride

Finasteride for Women

Although the involvement of androgens in female pattern hair loss is less clear, there is data that suggests that finasteride can be effective off-label treatment for some women. This article answers commonly asked questions about whether women can take finasteride for hair loss, the best dosage of finasteride for women, whether the treatment is safe for female patients, and common side effects.

Finasteride

Finasteride Side Effects in Women

Finasteride is a long-standing treatment option for men experiencing pattern hair loss and has gained more attention recently as a potential medication for female pattern hair loss. The drug’s mechanism of action and effects on androgen levels have been linked to possible side effects in male patients, leaving female patients to wonder if they need to be cautious of the same risks. This article covers frequently asked questions about the safety and side effects of finasteride for women.

Minoxidil

Oral Minoxidil vs Topical

The decision to choose oral minoxidil vs topical can depend on several factors including tolerance for the medication and severity of hair loss is. In some cases, patients have demonstrated a better response to oral minoxidil which may attributed to differences in drug metabolism. This article takes a closer look at differences between minoxidil formats and the current clinical evidence comparing safety and efficacy.

Dutasteride

Dutasteride Mesotherapy

Mesotherapy is a technique that is thought to improve the efficacy of topical medications via increased penetration of topical medications and triggering wound repair. This article discusses the use of mesotherapy in conjunction with the 5-alpha reductase inhibitor dutasteride, comparisons to microneedling, safety and efficacy, as well as cost.

Pattern hair loss basics

Female Pattern Hair Loss

Female pattern hair loss (FPHL) is a progressive hair loss disorder that typically affects women as they age. It’s not clear exactly what triggers it, but hormonal changes (specifically, decreased estrogen during and after menopause) may play a role. This article discusses what female pattern hair loss is, who it affects, and management options.

Minoxidil

Minoxidil For Women

Minoxidil is FDA approved to treat female pattern hair loss as a topical foam or solution at concentrations of 2% and 5%. However, oral minoxidil has emerged as an off-label alternative. This article discusses minoxidil side effects in women, whether minoxidil works for female pattern hair loss, and what women can expect when taking this medication to help minimize hair loss and promote hair growth.

Minoxidil

Minoxidil Shedding

Minoxidil is commonly used to treat male and female pattern hair loss. Like other hair loss medications, starting minoxidil can cause a period of temporary shedding commonly attributed to transitioning hair follicles into a new hair growth cycle. This article discusses why this occurs, how long this shedding lasts, and when to consult a physician.

Finasteride

How Long Does Finasteride Take To Work?

This article covers frequently asked questions about how long finasteride takes to work for hair loss and benign prostatic hyperplasia (BPH). Typically, finasteride starts to have an effect on DHT within weeks of starting the medication. For hair loss specifically, it can take several months before the full effect of the medication can be evaluated. While patients wait for these results, adherence to treatment is encouraged to maintain progress.

Finasteride

Can Finasteride Regrow My Hairline?

A receding hairline is a common concern for many men experiencing pattern hair loss. It can also be more challenging to treat when compared to thinning at the top of the head. This article discusses whether finasteride can be an effective treatment for this region of hair loss and when to start treatment for best results.

Minoxidil

Minoxidil Side Effects

Minoxidil is available in different forms, some of which can be purchased over the counter (e.g., certain topical concentrations and formats), while others require a prescription (off-label oral formats). Like almost any medication, minoxidil has potential side effects that may be affected by delivery method and concentration.

Dutasteride

Dutasteride 0.5 mg Capsule

Dutasteride can be prescribed off-label in North America at a dose of 0.5 mg to treat hair loss in men. This article covers the cost and possible side effects of the 0.5 mg dose of dutasteride, the best time to start this medication, as well as potential side effects and other key safety considerations.

Minoxidil

Rosemary Oil vs Minoxidil

The rosemary plant (and more specifically, rosemary extract) has been shown to have anti-inflammatory, antioxidant and even anti-tumor activity in laboratory experiments. Increasingly, it's gained attention as a potential adjunct for thinning hair and is an ingredient in many natural hair loss solutions. This article summarizes the available literature on rosemary extract for pattern hair loss and compares it to the more established medication, minoxidil.

SiloxysSystem technology

Topical Dutasteride Clinical Data

SiloxysSystem™ Gel was developed to deliver medications such as dutasteride in a precise and highly targeted way, helping to lower systemic absorption. This report summarizes the in-vitro investigations and data that provide evidence for the gel's ability to control release and improve skin retention of dutasteride.

Dutasteride

Switching From Finasteride to Dutasteride

With a growing body of evidence to support its efficacy and potency compared to finasteride, dutasteride is increasingly being prescribed off-label to treat pattern hair loss. If you’re already taking finasteride, is there a good reason to switch to dutasteride? And is there anything you should know before switching over? This article discusses the potential benefits and drawbacks of switching between these hair loss treatments.

Finasteride

Can I Buy Finasteride Over the Counter?

While there are many over-the-counter solutions for thinning hair, the treatments that have the biggest impact require a prescription. This article covers frequently asked questions about whether finasteride can be bought over-the-counter, where and how to buy finasteride, and provides examples of alternative hair loss solutions for people who aren't able to access, or aren't interested in prescription options.

Complementary care

Saw Palmetto for Hair Growth

Saw palmetto has gained attention as a possible adjunctive treatment for androgenetic alopecia (male pattern hair loss). This natural extract is said to have DHT-blocking properties that may help slow down and stop the progression of this type of hair loss. However its potency, dosing, and long-term safety compared to dedicated 5-alpha reductase inhibitors such as finasteride are unclear.

Pattern hair loss basics

Male Pattern Baldness Gene

Pattern baldness is most likely inherited as a polygenic trait, meaning multiple gene variations are involved that can come from either side of the family. This article delves deeper into the inheritance pattern of androgenetic hair loss, whether these can be used to predict when hair loss will strike, and strategies for prevention.

Dutasteride

Dutasteride for Female Hair Loss

Dutasteride is a medication that can be used off-label to treat pattern hair loss in men, cicatricial (scarring) alopecia and in some cases, female pattern hair loss. There is clinical evidence that suggests it may be more effective than finasteride for male patients, but is this also the case in female patients? Is dutasteride safe for female hair loss? We address these questions and more in this article.

Finasteride

Finasteride Mechanism of Action

Finasteride's mechanism of action involves binding to the 5 alpha-reductase enzyme and preventing conversion of testosterone to dihydrotestosterone (DHT). This article takes a closer look at the effect of finasteride on scalp and prostate tissues.

Finasteride

Finasteride for Hair Loss

Finasteride is commonly prescribed at a 1 mg oral dose for male hair loss. It is a 5-alpha reductase inhibitor that blocks formation of the androgen dihydrotestosterone (DHT), widely regarded as the primary cause of male pattern hair loss. This article is a detailed explainer about what types of hair loss can be treated with finasteride, finasteride's efficacy, and whether it stays effective in the long term. Also discussed are issues of the timing of finasteride treatment and whether it needs to be taken indefinitely to maintain results.

Finasteride

Finasteride and Pregnancy

For many patients considering finasteride, family planning is a key concern. The medication is a known teratogen. This article talks about what patients needs to know about finasteride and risks for pregnancy, whether finasteride causes birth effects, if it should be stopped before pregnancy, and best practices for safe handling. Patients are encouraged to talk their doctor about any concerns around finasteride use and pregnancy.

Finasteride

Finasteride Interactions

Before starting finasteride, it’s important to talk to a licensed healthcare provider about possible drug interactions. This article covers examples of common medications and substances and their potential interactions with finasteride. Broadly speaking, finasteride has not been associated with significant drug interactions.

Dutasteride

Dutasteride Cost

Dutasteride is a newer generation of 5-alpha reductase inhibitor that has not yet been approved by the FDA or Health Canada for the treatment of male pattern hair loss. Based on available data, it may be more potent compared to finasteride and is a potential off-label alternative for patients who do not respond to finasteride. This article addresses common questions about the cost of dutasteride, reasons for why dutasteride is generally more expensive than finasteride, and why compounded formulations of dutasteride cost more.

Causes of hair loss

Causes of Hair Loss

While DHT is associated with pattern hair loss, it's important not to overlook other possible causes of hair loss such as poor diet and nutrition, underlying medical conditions or medication use, as well as stress and other lifestyle factors. This article discusses some of the most common causes of thinning that are not androgen-mediated.

Dutasteride

Dutasteride Side Effects

Dutasteride is a potent 5-alpha reductase inhibitor that can be prescribed off-label to treat male pattern hair loss. Like other medications used to treat hair loss, there are possible side effects. This article discusses common side effects associated with dutasteride use, whether these are permanent, and strategies for mitigating risk.

Finasteride

Post-Finasteride Syndrome

Post-finasteride syndrome (PFS) refers to a constellation of symptoms that can include long term sexual, neurological and/or physical side effects that persist even after stopping finasteride. It's considered a possible serious side effect, although strict diagnostic guidelines have yet to be established. Currently, there is debate within the medical community about whether PFS is a "real" syndrome, but patients who are experiencing these kinds of side effects after taking finasteride are encouraged to speak with their doctor.

Science of hair

How Does Hair Grow? The Hair Growth Cycle

The hair growth cycle describes the various stages and their respective timeframes leading up to the production of a visible strand of hair. It involves three main stages: anagen (active growth), catagen (regression) and telogen (rest). Dysregulation of the hair growth cycle can lead to premature hair thinning and hair loss. This article discusses the main stages of the hair growth cycle, anatomy of the hair follicle, as well as which hair loss disorders are most likely during each of these stages.

Pattern hair loss basics

What Is Androgenetic Alopecia?

Androgenetic alopecia (AGA) is a form of hereditary hair loss that typically results in balding along the hairline, temples, and the top of the head. It's a progressive condition that can start anytime after puberty and affects approximately 50% of men by the age of 50, with a higher incidence among Caucasian men. It's primarily caused by the androgen dihydrotestosterone (DHT) and can be managed through the use of 5-alpha reductase inhibitors such as finasteride.

Pattern hair loss basics

What is the Hamilton-Norwood scale?

These patterns of shedding observed with androgenetic alopecia (male pattern hair loss) have been formalized in a clinical scale called the Norwood scale. The scale consists of 7 main stages of hair loss with several other distinct variants. It is an important tool that can be used to help assess severity and progression of hair loss, and guide which interventions are likely to help.

Causes of hair loss

Does Working Out Cause Hair Loss?

Regular exercise is essential to maintaining optimal health. But does working out also cause hair loss? Fortunately, current research suggests that in most cases, the answer is no. This article explores what happens to the body during exercise, whether the associated physiological and biochemical changes have an effect on hair, and what role pre and post-workout nutrition might play in hair growth.

Causes of hair loss

Hormones and Hair Loss: Hypothyroidism

Thyroid hormone imbalances have been associated with hair loss. This article provides an overview of how thyroid hormones work, their role in the hair growth cycle and thinning, how to tell if hair loss may be due to a thyroid imbalance, and what to do about it.

Causes of hair loss

Does Testosterone Cause Hair Loss?

Although testosterone is an androgen related to dihydrotestosterone, it does not directly cause pattern hair loss. This article provides a refresher on what actually causes androgenetic hair loss, whether testosterone replacement therapy (TRT) increases the risk for hair loss, and strategies for preventing or managing hair loss.

Science of hair

Scalp Health: 101

This article covers topics like how to recognize a healthy scalp, why it’s important to take care of scalp skin, and provides practical tips that people can implement everyday. Scalp health is important because research has shown that hair growth can be influenced by the health and biochemical environment of the scalp.

Finasteride

Finasteride Shedding

Finasteride shedding refers to an sudden increase in hair loss that begins shortly after starting finasteride, or any other hair loss treatment. It is a normal response attributable to changes in the hair growth cycle. This articles examines what finasteride shedding is, when it typically begins and stops, and what to do about it.

Science of hair

Scalp Anatomy: The 5 Layers Of The Scalp

The scalp contains five layers that vary in function, form and cellular composition. It contains a complex network of connective fibers, blood vessels, nerves, hair follicles, and other connective fibers. The scalp is also how oxygen and nutrients access developing hairs and where hair loss medications such as topical finasteride are active.

Finasteride

Stopping Finasteride

Finasteride is an effective treatment for male pattern hair loss but patients may need to take the medication indefinitely. Currently available study data supports the long term safety of finasteride This article helps answer some frequently asked questions about what happens when stopping finasteride and the potential impacts of hair growth and treatment progress.

Finasteride

Still Losing Hair On Finasteride

Although it’s a highly effective treatment for androgenetic hair loss (male pattern hair loss), there are some patients who will continue to lose their hair while taking finasteride. This article discusses possible reasons for why patients may still be losing hair on finasteride, whether taking finasteride can worsen existing hair loss, and what patients can do if they are continuing to lose hair while on finasteride.

Finasteride

What Is The Optimal Finasteride Dosage for Hair Loss?

Finasteride is FDA approved to treat pattern hair loss at an oral dose of 1 mg daily. However, compounded topical formulations are growing in popularity, driven by patient concerns about the risk for potential systemic side effects. This article discusses the various considerations that go into determining optimal finasteride dosage for topical formats and the effect of different carriers and vehicles on resultant concentration.

Dutasteride

Dutasteride for Hair Loss

Dutasteride has been used for decades to treat benign prostatic hyperplasia (BPH) in men. More recently, this drug is increasingly being prescribed off-label for male pattern hair loss. It's mechanism of action is similar to finasteride, with the primary difference being more complete DHT blockade (it blocks two isoforms of 5-alpha reductase instead of one). This article provides a high level summary of some of these key differences.

Pattern hair loss basics

What Is The Best Medication For Hair Loss?

Minoxidil, finasteride, and dutasteride are some of the most recognizable and prescribed pharmaceutical agents for hair loss. This article discusses the various different mechanisms through which they prevent hair loss and support healthy hair growth, FDA approval status, and safety information. The best medication is one that meets the needs of the patient and balances potential benefits and risks.

Finasteride

Liposomal Finasteride Gel

Liposomal finasteride can be an effective solution for thinning hair. This article explains what liposomal finasteride gel is, how it works, possible benefits, and the differences between various formulations. In general, these types of formulations are designed to increase permeation of finasteride and promote uptake of this ingredient into scalp skin.

Complementary care

6 Best Natural Ingredients for Hair Growth

Natural ingredients are a potential alternative solution for individuals who are unable or not ready to pursue pharmacological treatment for hair loss. This article provides an overview of six of the best natural ingredients for hair growth and explains how they can potentially support hair and scalp health via mechanisms such as increased blood flow to the scalp, antioxidant and anti-inflammatory properties, or DHT-blocking capabilities.

Finasteride

Finasteride 5mg vs 1mg

Finasteride 5 mg is not approved for the treatment of male pattern hair loss. For most patients, the 1 mg dose of finasteride is sufficient to produce a good treatment results while keeping the risk of developing side effects low. It's not known whether increasing the dose of finasteride is beneficial. This article explores common questions around the efficacy, safety, and economics of the higher 5 mg dose of finasteride versus the approved 1 mg dose.

Complementary care

Rosemary Oil For Hair Growth

Early data has shown that rosemary oil and extracts may help promote scalp and hair follicle health due to the presence of antioxidants and anti-inflammatory agents. This article discusses the possible benefits and risks of using rosemary oil for hair growth and hair loss prevention, and provides an explanation for the theoretical mechanisms behind these processes.

Complementary care

Red Clover Extract for Hair: Can Red Clover Help Regrow Hair?

Trifolium pratense (red clover) extract may help stimulate hair growth, thicken hair, and decrease scalp inflammation. Available data suggests that it maybe be a useful adjunctive ingredient. This article discusses the active compounds in red clover as well as clinical evidence for its safety and efficacy.

Complementary care

Saw Palmetto Shampoo: Does It Help With Hair Loss?

Saw palmetto is purported to have anti-androgenic properties and the ability to reduce levels of male sex steroid hormones such as DHT. Because of this property, saw palmetto may be useful in the treatment of health conditions associated with elevated levels of DHT, such as androgenetic hair loss. This article considers its use in shampoo formulations, whether it helps with thinning, and safety considerations.

Finasteride

Finasteride vs Minoxidil: Which is Better for Your Hair Loss?

Finasteride and minoxidil are two of the most well-known pharmaceuticals used to treat androgenetic alopecia. This article summarizes key differences in mechanism of action, efficacy and side effects. Literature suggest that in some cases, there may be benefits gained from using finasteride and minoxidil in combination.

Complementary care

Saw Palmetto vs Finasteride

Saw palmetto has gained attention in recent years as a natural DHT-blocking agent, with potential applications for male pattern hair loss and benign prostatic hyperplasia (BPH). This article covers key differences between saw palmetto and finasteride mechanisms of action, efficacy, and safety in the treatment of hair loss.

Causes of hair loss

Prevent Hair Loss While Sleeping

This article highlights the top five ways to prevent hair loss while sleeping. Tips include strategies to lower the risk of hair breakage, reduce damage to hair follicles, and combat hair loss for those at risk thinning or current hair loss sufferers.

Finasteride

Finasteride Side Effects

Oral finasteride was first approved for the treatment of androgenetic alopecia (male pattern hair loss) in 1997. While extensive safety studies have been conducted on finasteride and its safety profile is well-characterized, the medication continues to attract attention for possible sexual side effects and more worryingly, an increase in the risk for suicidal ideation. This article examines what the most common side effects are and what to do if patients believe they may be experiencing them.

SiloxysSystem technology

XYON Health Clinical Data: SiloxysSystem™ Gel

SiloxysSystem™ Gel is XYON's patented delivery technology, developed to help reduce systemic absorption of medications such as finasteride. Unlike other topical vehicles, studies show that it controls release of drug molecules and improves skin retention. This report summarizes the in-vitro data for finasteride compounded in SiloxysSystem™ Gel.

Pattern hair loss basics

DHT and Hair Loss

DHT (dihydrotestosterone) is the male sex steroid hormone primarily responsible for male pattern hair loss. DHT levels are modulated by DHT production and metabolism, which are processes dictated by genetics. This article discusses what DHT is, the role that it plays in human biology, and provides a high level explanation of its involvement in the development and progression of pattern hair loss.