Prescription Required

Oral Spironolactone for Hair Loss in Females

Stop hormonal hair loss and regrow your hair with this prescription solution for thinning hair in women. With just one pill a day, clinically-proven oral spironolactone lowers levels of the hormone known to cause pattern hair loss and reduces its impact on hair follicles. The result? Thicker, healthier hair.

* This page was medically reviewed by Dr. Christina Han, MD FRCPC

* Oral spironolactone has not been approved by the FDA for the treatment of female pattern hair loss. Only available if prescribed after an online consultation with a licensed healthcare provider.

How Does Spironolactone for Female Hair Loss Work?

Studies have shown that spironolactone stops hair loss from worsening and gives hair a chance to regrow in 70-80% of cases of female pattern hair loss (Sinclair et al., 2005 and Famenini et al., 2015). Unlike other medications commonly used to treat female pattern hair loss, spironolactone works in two unique ways.

XYON illustration showing oral Spironolactone blocking hormone production in hair follicles

Block Hormone Production

DHT, a hormone that triggers pattern hair loss, is made from testosterone. Spironolactone prevents this from happening by reducing testosterone production.

XYON illustration showing oral Spironolactone blocking DHT in hair follicles

Reduce Hormonal Effects

To take effect, DHT needs to bind with specific areas of the hair follicle. Spironolactone stops this from happening by binding first and blocking access to these areas.

Does Spironolactone Work for Female Hair Loss?


of women receiving oral anti-androgens showed no progression or improvement of their hair loss.

Sinclair et al., 2005


of case-study patients taking spironolactone experienced a reduction in hair loss and an increase in anagen hairs.

Adamapoulos et al., 1997

How To Use Spironolactone for Female Hair Loss

Here are some best practices for making the most of your hair loss treatment.

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