Prescription RequiredHair Loss Treatment

Spironolactone Tablets for Women

Sale price$29.00 per month

(Delivered every 3 months)

Stop hormonal hair loss and regrow your hair with this prescription solution for thinning hair in women. With just one pill a day, clinically-proven oral spironolactone lowers levels of the hormone known to cause pattern hair loss and reduces its impact on hair follicles. The result? Thicker, healthier hair.

Important Safety Information

Before you start using spironolactone and each time you get a refill, please review this important safety information. There may be new information. This information does not replace discussing your medical condition or treatment with your healthcare provider.

What is the FDA-approved use of spironolactone?

Spironolactone is FDA-approved as an oral medication to treat hypertension (high blood pressure), heart failure, certain types of edema (fluid retention) and primary hyperaldosteronism.

Spironolactone has not been FDA-approved for the treatment of polycystic ovarian syndrome (PCOS) or female pattern hair loss but is commonly prescribed off-label to treat these conditions.


What should I tell my healthcare provider before taking spironolactone?

Let your doctor know if you have any of the following conditions before you begin taking spironolactone:


Addison's disease (e.g., adrenal problem)

Kidney disease

Electrolyte or fluid imbalances (e.g., hyperkalemia)

Liver disease

You are pregnant or trying to get pregnant

You are breastfeeding

You are taking another blood pressure medication, such as eplerenone


Who should not take spironolactone?

Do not take spironolactone if you:

Have ever had an allergic reaction to spironolactone

Have a history of liver disease or dysfunction

Have a history of kidney disease or dysfunction

Spironolactone should not be used by women who are pregnant or may be pregnant

Spironolactone should not be used by women who are breastfeeding

Spironolactone should not be used by infants or children


Please be aware that withholding or providing inaccurate information about your health and medical history in order to obtain treatment may result in harm, including, in some cases, death.


What warnings and precautions should I be aware of before starting spironolactone?


Pregnancy and Breastfeeding: Spironolactone is a pregnancy category C medication. This medication has been found to cause birth defects in animal studies, but there have been no adequate and well-controlled human studies to ascertain risk. As it stands, the potential benefits of using spironolactone may outweigh the potential risk in pregnant women. Patients are encouraged to talk to their doctors and take precautions as necessary. Spironolactone is also known to pass through breastmilk, though its impact on infant health is unclear.


Hyperkalemia (High Blood Potassium) Levels: Spironolactone may cause hyperkalemia. Signs of hyperkalemia include confusion, difficulty breathing or irregular heartbeat, nausea and vomiting. Please consult your doctor immediately if you experience any of these symptoms.


Electrolyte Imbalance: Because spironolactone affects fluid retention, this medication may cause electrolyte imbalances. Examples of electrolytes include sodium and calcium. This medication may also cause changes in blood sugar levels. Please contact your doctor if you become ill while taking this medication (e.g., severe nausea, vomiting, diarrhea) or engage in exercise that involves heavy sweating, as there is a risk that you may lose too many electrolytes and your blood pressure may become too low.


Drug Interactions


The following is a list of medications that may interact with spironolactone:


Diuretics (water pills)

Potassium supplements

Blood pressure medications (e.g. ACE inhibitors)


Digoxin (used to treat some heart conditions)

Certain antibiotics


This is not a complete list of medications that may interact with spironolactone. Please let your doctor know about any other medications or supplements you may be taking.


Side Effects


Serious side effects from spironolactone when taken as directed are uncommon. A systematic meta-analysis and review of the safety of spironolactone for the off-label treatment of pattern hair loss can be found here ( The following adverse effects have been reported with spironolactone use:

High blood potassium levels

Low blood pressure

Electrolyte imbalances

Leg cramps

Gynecomastia (breast swelling) or breast tenderness/pain

Menstrual irregularities

Lethargy and drowsiness

Dizziness and/or headache

Confusion, lack of coordination

Loss of libido

Feminization (in male patients)

The above list does not represent all potential side effects, medication interactions or study data relating to the safety of minoxidil. Unreported or unexpected side effects might exist. It is important to talk to your doctor, healthcare provider and/or pharmacist if you are experiencing any side effects.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of spironolactone. For more information, ask your healthcare provider or pharmacist.


If you are experiencing a medical emergency, call 911 or seek immediate medical attention.


You are encouraged to report negative side effects of prescription products to the FDA. Visit or call 1-800-FDA-1088.


Additional information can be found in the Prescriber’s Digital Reference (PDR) for spironolactone:




* This page was medically reviewed by Dr. Christina Han, MD FRCPC

* Oral spironolactone has not been approved by the FDA for the treatment of female pattern hair loss. Only available if prescribed after an online consultation with a licensed healthcare provider.

How does it work?

Treating female hair loss with spironolactone.

For 70-80% of women experiencing female pattern hair loss, spironolactone has been proven to stop it from worsening and give hair a chance to regrow. The result? Thicker, healthier hair.

XYON illustration showing oral Spironolactone blocking hormone production in hair follicles

Blocking hormone production

It reduces the production of male hormones like testosterone and dihydrotestosterone (DHT), which can trigger pattern hair loss.

XYON illustration showing oral Spironolactone blocking DHT in hair follicles

Reducing hormonal effects

It stops DHT from binding to hair follicles and shrinking them to the point where they can no longer produce healthy hair.

Other women are seeing results with spironolactone.


experienced a reduction in hair loss and increased hair growth.

Resources designed with you in mind.

The first stop in any hair loss journey is getting the information you need on potential causes and treatments. That’s why, we’ve worked with our knowledge experts to provide tailored guidance and answers on a variety of hair loss topics to help you move forward, confidently. 

Stress-free care for you and your hair.

We’ve designed our process to ensure your treatment journey is simple and straightforward at every stage. 

Easy Online Process

Get specialist support when you want it, at times that suit you.

Expert Solutions 

Access world-class treatments made to meet and solve your individual needs. 

Effortless Delivery

Set it and forget it. We take care of shipping your prescription and refills.