Prescription Required2-in-1 Hair Loss Treatment

Topical Finasteride and Minoxidil

Sale price$119.00 per month

(Delivered every 3 months)

Clinically-effective hair loss treatments finasteride and minoxidil are combined in a patented liposomal gel, designed to target hair loss medications directly to the scalp and hair follicles.  Formulated by doctors to release medications slowly, which may limit absorption into the body. Increased hair regrowth potential, mess-free application. Dermatologist tested.

Safety Information

Before you start using finasteride and minoxidil and each time you get a refill, please review this important safety information. This information may be updated. It does not replace discussing your medical condition or treatment with your doctor or healthcare provider. Safety information for both finasteride and minoxidil is contained within this document. Please take care to review this entire document.

What is the FDA approved use of finasteride?

  • Finasteride is FDA-approved as an oral medication to treat benign prostatic hyperplasia (Proscar) and androgenetic alopecia (Propecia) in men.
  • Finasteride has not been FDA-approved for topical use in men or women. However, it may be prescribed off-label in topical compounded formulations to treat hair loss. Please note that oral finasteride has also not been approved for use in women, for any indication.


What is the FDA approved use of minoxidil?

  • Topical minoxidil is FDA approved at concentrations of 2% and 5% as topical formulations to treat hair loss in women and men (Rogaine®). All other topical compounded strengths of minoxidil are considered off-label uses.
  • Oral minoxidil is FDA-approved for the treatment of symptomatic high blood pressure. Low-dose oral minoxidil may be prescribed off-label to treat hair loss.


What is topical finasteride and minoxidil?

Topical finasteride and minoxidil is a compounded prescription medication used for the treatment of male and female pattern hair loss (androgenetic alopecia). This compounded treatment is not approved by the FDA and is only available if prescribed after an online consultation with a licensed physician through the XYON Health platform.

Data from small scale and case studies suggests that taking finasteride in combination with minoxidil may increase the effectiveness of hair loss treatment in some patients. This may be due to different mechanisms of action that help address the various causes of pattern hair loss.


What should I tell my healthcare provider before taking finasteride and minoxidil?

Please inform your doctor or healthcare provider if any of the following apply:

  • You have a personal or family history of prostate cancer, breast cancer
  • You have prostate or urinary symptoms such as reduced urine flow, difficulty urinating or pain
  • You have a history of heart conditions (e.g., high blood pressure, heart failure, previous heart attack, pericarditis, abnormal heart rhythm, chest pain/angina)
  • You have a history of vascular conditions (e.g., stroke, severe lower leg swelling, pulmonary hypertension)
  • You have a history of liver or kidney disease or dysfunction
  • You have a history of any serious mental health conditions
  • You are pregnant, trying to get pregnant, or are breastfeeding

You should be aware that minoxidil has the potential to be toxic to some animals. Please ensure that pets do not come into contact with minoxidil or lick your hands after application.


Who should not take finasteride and minoxidil?

You should not take finasteride and minoxidil if you: 

  • Have ever had an allergic reaction to finasteride, minoxidil or any other ingredients in the treatment
  • Have a history of liver disease or dysfunction
  • Finasteride and minoxidil should not be used by women who are pregnant, may be pregnant or are breastfeeding
  • Finasteride and minoxidil should not be used by infants or children

Black box warning: Serious cardiac effects associated with oral minoxidil

  • Oral minoxidil has a black box warning because the medication is a powerful antihypertensive agent. Serious cardiovascular side effects have been observed in clinical trials where the drug has been used to treat symptomatic high blood pressure. When used off-label for hair loss, oral minoxidil is typically dosed at less than 5mg to help reduce the likelihood of experiencing an adverse cardiovascular event
  • Oral minoxidil can cause pericardial effusion, which can progress to a condition called tamponade which increases pressure on the heart and keeps it from beating properly. This can result in sharp chest pain and difficulty breathing. Seek emergency treatment if this occurs
  • Chest pain warning: Minoxidil can increase your heart rate and cause or worsen chest pain. If you have new or worsening pain in the chest, arm, or shoulders, tell your doctor right away or go to the nearest emergency department.
  • Heart function warning: Minoxidil can cause poor heart function or worsen existing heart problems like heart failure. When tested on animals, minoxidil caused several kinds of lesions of the heart muscle as well as other adverse heart effects. Patients with malignant hypertension and those already receiving guanethidine should be hospitalized when minoxidil is first administered so that they can be monitored to avoid too rapid or large decreases in blood pressure

What are the possible side effects of finasteride and minoxidil?

The following side effects have been reported with finasteride use:

  • Breast tenderness and enlargement. You should inform your doctor or healthcare provider if you notice any breast lumps, pain or nipple discharge
  • Depression, anxiety, brain fog, suicidal ideation
  • Decrease libido (sex drive)
  • Allergic reactions (e.g., rash, itching, hives and swelling of the lips, tongue, throat, and face)
  • Problems with ejaculation
  • Testicular pain
  • Erectile dysfunction (difficulty achieving or maintaining an erection)
  • Male infertility and/or poor semen quality

Please note that finasteride has only been formally studied in male patients, so the side effect profile above is specific to clinical studies in men. Preliminary data on the use of finasteride in female patients has shown the following possible side effects:

  • Decreased libido (sex drive)
  • Breast tenderness and enlargement
  • Mood changes (e.g., depression)
  • Fatigue
  • Muscle soreness
  • Weight gain

There is some evidence that finasteride can increase the risk of some breast and prostate cancers.


When used off label in a topical form, systemic side effects of finasteride and minoxidil are expected to be less frequent/severe. The following is a list of possible side effects associated with the use of topical finasteride:

  • Itching
  • Irritation
  • Dry and flaky scalp
  • Increased scalp oiliness

The following side effects have been reported with topical minoxidil use:

  • Itchy scalp or skin rash
  • Dryness, scaling, or flakiness
  • Redness or irritation at the application site

The above lists do not represent all potential side effects, medication interactions or study data relating to the safety of finasteride and minoxidil. It is important to talk to your doctor, healthcare provider and/or pharmacist if you are experiencing any side effects. A comprehensive review of the potential safety risks of using finasteride and other similar medications can be found at this link: A review of minoxidil, its clinical applications and safety can be found at this link: If you are experiencing a medical emergency or allergic reaction, call 911 or seek immediate medical attention. You are encouraged to report negative side effects of prescription products to the FDA. Visit or call 1-800-FDA-1088. Additional safety information can be found here, in the Digital Prescriber’s Reference for finasteride: and Digital Prescriber’s Reference for oral minoxidil:

* This page was medically reviewed by Dr. Christina Han, MD FRCPC.

* Topical finasteride and minoxidil is a compounded medication and has not been approved by the FDA. Only available if prescribed after an online consultation with a licensed healthcare provider.

US Pat. no. 11,786,466

SiloxysSystem™ Gel

Our patented gel technology is changing the way hair loss is treated. Designed to deliver medications over time, the gel works to help limit absorption into the body. The result? A potentially safer way to combat the effects of thinning hair or balding.

Learn About SiloxysSystem™

Better together.

How finasteride and minoxidil treat hair loss.

Studies show that combining finasteride with minoxidil may be superior to using either treatment alone. Here's how.

Pause Hair Loss

In genetically predisposed men, high levels of DHT can trigger hair loss and cause hair follicle shrinkage. Finasteride blocks production of DHT to slow this process and encourage regrowth.

Boost Hair Growth

Minoxidil increases blood flow and nutrient exchange to the scalp. It also stimulates the active growth phase of the hair growth cycle, for thicker, longer hair.

Results That Last

By addressing the root causes of hair loss and creating conditions for optimal hair growth, your hair follicles are kept healthy for as long as possible.

Real hair growth results.

XYON Topical Finasteride and Minoxidil: before and after.

See what this XYON user has been able to achieve using our combined topical finasteride and minoxidil formulation.

See our customer reviews ▸




Does topical finasteride and minoxidil work for men?

Early clinical trials and case studies have shown that using finasteride plus minoxidil together to treat pattern hair loss may be more effective, with a similar risk of side effects to taking finasteride or minoxidil alone.


of men taking a combination topical therapy containing finasteride and minoxidil experienced clinical improvement in hair loss.

Rai et al., 2018


of patients who switched from oral to topical finasteride and minoxidil maintained their hair density.

Chandrashekar et al., 2015


of patients taking finasteride and minoxidil experienced moderate to marked improvement in hair density, diameter and photographic assessment.

Suchonwanit et al., 2018

Designed to reduce side effects of finasteride and minoxidil.

Clinical trials have shown that finasteride and minoxidil can be an effective treatment option for pattern hair loss. Since being FDA-approved, oral finasteride has been associated with sexual side effects and mood changes, as well as an increased risk of some prostate cancers (Hirshburg et al., 2016), while the most common side effect of topical minoxidil is skin irritation. See how XYON's patented SiloxysSystem technology is designed to lower the risk of these potential side effects.

Learn More About SiloxysSystem™
SiloxysSystem™ Gel - XYONHealth

SiloxysSystem™ Gel

Topical Finasteride Sprays & Solutions - XYONHealth

Sprays & Solutions




Designed to reduce absorption of medications into the body and lower risk of side effects by targeting delivery of treatments to the scalp and keeping them there.

Medication delivery is uncontrolled; may contain ingredients that promote absorption, potentially increasing risk of side effects.

Exposes the whole body to medications, possibly increasing the risk of side effects.

Delivery System

Medications released over time to maximize hair follicle uptake. Drip-free formula and lightweight texture. Hydrating gel base.

No sustained delivery. Messy formulas may require multiple applications per day to be effective. Alcohol-based ingredients can cause skin irritation.

A pill, taken by mouth. A good option for those less concerned about side effects.

Application tips for XYON Topical Finasteride and Minoxidil.

Maximize the results of your hair loss treatment with these application tips.

Visit the XYON medical library.

Stay up to date with our curated selection of medically-reviewed articles and resources on men's health and hair loss.

Frequently asked questions about topical finasteride and minoxidil.

Here are some common queries we've received about topical finasteride and minoxidil for hair loss.

How to get topical finasteride and minoxidil from XYON.

When you choose XYON for your hair loss needs, you'll also receive these additional benefits.

Access to Doctors

Every case is reviewed by a specialist physician who will use the info you provide during your intake to recommend an ideal treatment.

Personalized Hair Solutions

Every hair loss case is unique. We've partnered with compounding pharmacies that specialize in preparing customized solutions for patients.

Deliveries to Your Door

If the doctor decides you need a prescription, we'll take care of deliveries and refills. It's an easier and faster way to manage hair loss.