Prescription RequiredHair Loss Treatment

Topical Dutasteride for Women

Sale price$129.00 per month

(Delivered every 3 months)

Treat postmenopausal hair loss and thinning hair in women with dutasteride. Clinically-proven to help restore hair thickness, density and vitality. Delivered with an advanced physician-formulated, timed-release gel designed to minimize absorption of medication into the body. Dermatologist tested.

Safety Information

Before you start using dutasteride and each time you get a refill, please review this important safety information. This information may be updated. It does not replace discussing your medical condition or treatment with your doctor or healthcare provider.

What is the FDA approved use of dutasteride?

Dutasteride is FDA approved as an oral medication to treat benign prostatic hyperplasia (Proscar) in men. Dutasteride has not been FDA approved for topical use or specifically for use in women, but it may be prescribed off-label in topical compounded formulations for hair loss.

You can read more about some of the study data on dutasteride use in women by visiting this link:

Adverse effects and safety of 5-alpha reductase inhibitors finasteride and dutasteride: A systematic review.

What is topical dutasteride?

Topical dutasteride is a compounded prescription medication used for the treatment of male and female pattern hair loss (androgenetic alopecia). This compounded treatment is not approved by the FDA and is only available if prescribed after an online consultation with a licensed physician through the XYON Health platform. Data from small scale and case studies have shown that topical dutasteride may help reduce serum DHT levels with a lower incidence of side effects (e.g., sexual dysfunction) that have been reported with the oral versions of this class of medications.

What should I tell my healthcare provider before taking dutasteride?

Please inform your doctor or healthcare provider if any of the following apply:

  • You have a personal or family history of prostate cancer, breast cancer
  • You have prostate or urinary symptoms such as reduced urine flow, difficulty urinating or pain
  • You have a history of liver or kidney disease or dysfunction
  • You have a history of any serious mental health conditions
  • You are pregnant, trying to get pregnant, or are breastfeeding

Who should not take dutasteride?

You should not take dutasteride if you:

  • Have ever had an allergic reaction to dutasteride or any other ingredients in the treatment
  • Have a history of liver disease or dysfunction
  • Dutasteride should not be used by women who are pregnant, may be pregnant or are breastfeeding
  • Dutasteride should not be used by infants or children

What are the possible side effects of dutasteride?

The following side effects have been reported with dutasteride use:

  • Breast tenderness and enlargement. You should inform your doctor or healthcare provider if you notice any breast lumps, pain or nipple discharge
  • Depression, anxiety, brain fog, suicidal ideation
  • Decrease libido (sex drive)
  • Allergic reactions (e.g., rash, itching, hives and swelling of the lips, tongue, throat, and face)
  • Problems with ejaculation
  • Testicular pain
  • Erectile dysfunction (difficulty achieving or maintaining an erection)
  • Male infertility and/or poor semen quality

Please note that dutasteride has only been formally studied in male patients so the side effect profile above is specific to clinical studies in men.

Preliminary data on the use of dutasteride in female patients has shown the following possible side effects:

  • Decreased libido (sex drive)
  • Breast tenderness and enlargement
  • Mood changes (e.g., depression)
  • Fatigue
  • Muscle soreness
  • Weight gain

There is some evidence that dutasteride can increase the risk of some breast and prostate cancers. When used off label in a topical form, systemic side effects of dutasteride are expected to be less frequent/severe, although no formal clinical studies have been done to confirm the safety and efficacy of topical dutasteride. The following is a list of possible side effects associated with the use of topical dutasteride:

  • Itching
  • Irritation
  • Dry and flaky scalp
  • Increased scalp oiliness

The above does not represent all potential side effects, medication interactions or study data relating to the safety of dutasteride. It is important to talk to your doctor, healthcare provider and/or pharmacist if you are experiencing any side effects. If you are experiencing a medical emergency or allergic reaction, call 911 or seek immediate medical attention. You are encouraged to report negative side effects of prescription products to the FDA. Visit or call 1-800-FDA-1088.
You can refer to the FDA prescribing information as well as the Prescriber’s Digital Reference (PDR) for comprehensive overviews of dutasteride.

* This page was medically reviewed by Dr. Christina Han, MD FRCPC.

* Topical Dutasteride is a compounded medication that is not FDA-approved. Dutasteride is not FDA-approved for use in women. Only available if prescribed after an online consultation with a licensed healthcare provider, for off-label use.

US Pat. no. 11,786,466

SiloxysSystem™ Gel

Made in Milan, our first-of-its-kind gel delivery system was developed to focus application of medications exactly where they're needed. Dutasteride is released slowly throughout the day, so you get a consistent dose without exposing the rest of the body. This minimizes the potential for side effects while delivering long-lasting results. 

About SiloxysSystem™ Gel

Does topical dutasteride work for women?


saw clinical improvements after 2 years of taking dutasteride.

Fabbrocini et al., 2018


reported thicker hair after taking dutasteride.

Boersma et al., 2014

xyon topical dutasteride for women DHT blocking illustration

How does topical dutasteride treat female hair loss?

For postmenopausal women experiencing thinning hair, dutasteride can be a powerful defensive solution. This is because hormonal changes associated with menopause can result in higher levels of DHT, which may accelerate hair loss by causing hair follicles to shrink. Dutasteride lowers DHT levels by blocking two forms of the enzyme that produce it. 

Is topical dutasteride safe to treat female hair loss?

Small-scale studies show that dutasteride is generally safe for menopausal women, but side effects are possible. It's important to be aware that doctors don’t recommend taking dutasteride if you’re pregnant, breastfeeding, or have a personal or family history of breast cancer. Choosing SiloxysSystem™ Gel technology is one way to lower the chance of side effects. 

Learn About SiloxysSystem™
SiloxysSystem™ Gel

SiloxysSystem™ Gel

Topical Finasteride Sprays & Solutions - XYONHealth

Sprays & Solutions




Targets medication where it’s needed, reducing absorption into the body.

Penetration-enhancing ingredients may increase absorption into the body, if included.

Exposes the entire body, increasing the possibility of side effects.


Timed release helps ensure consistent delivery of ingredients. Mess-free, lightweight gel.

Often messy and not targeted. May require several applications per day to be effective.

Impacts entire body as medication is taken orally and enters the bloodstream. 

Tips for using topical dutasteride.

Everything you need to know to get the best results from your treatment. 

Information you can trust.

We know hair loss can be scary and overwhelming. So, we’ve created a library full of articles that are reviewed by doctors and cover everything you need to know about causes of hair loss, treatments and general hair health.

A simple, straightforward, supportive process.

At XYON, you can quickly and easily get access to the hair solutions you need while enjoying peace of mind knowing our formulas are made by world-class physicians and scientists.

Convenient Care 

No waitlists, no lines. Simply share photos and info with a specialist physician online and they’ll create a treatment plan.

Personalized Prescriptions

Your hair is unique and so are our pharmacy partners. They specialize in providing custom made treatments.

Doorstep Delivery

Once you’ve got your prescription, you can sit back and relax. We’ve got delivery and refills covered.

Commonly asked questions about topical dutasteride for women.

Wondering what other women like you have been asking about dutasteride? Find out here.