Prescription Required2-in-1 Hair Loss Treatment

Topical Finasteride and Minoxidil for Women

Sale price$119.00 per month

(Delivered every 3 months)

Undo the first signs of thinning hair and hair loss in women with two doctor-recommended treatments in one. Finasteride and minoxidil are combined in an innovative patented gel designed to release medication over time and limit absorption of medication into the body. Mess-free application. Dermatologist tested.

Safety Information

Before you start using finasteride and minoxidil and each time you get a refill, please review this important safety information. This information may be updated. It does not replace discussing your medical condition or treatment with your doctor or healthcare provider. Safety information for both finasteride and minoxidil is contained within this document. Please take care to review this entire document.

What is the FDA approved use of finasteride?

  • Finasteride is FDA-approved as an oral medication to treat benign prostatic hyperplasia (Proscar) and androgenetic alopecia (Propecia) in men.
  • Finasteride has not been FDA-approved for topical use in men or women. However, it may be prescribed off-label in topical compounded formulations to treat hair loss. Please note that oral finasteride has also not been approved for use in women, for any indication.


What is the FDA approved use of minoxidil?

  • Topical minoxidil is FDA approved at concentrations of 2% and 5% as topical formulations to treat hair loss in women and men (Rogaine®). All other topical compounded strengths of minoxidil are considered off-label uses.
  • Oral minoxidil is FDA-approved for the treatment of symptomatic high blood pressure. Low-dose oral minoxidil may be prescribed off-label to treat hair loss.


What is topical finasteride and minoxidil?

Topical finasteride and minoxidil is a compounded prescription medication used for the treatment of male and female pattern hair loss (androgenetic alopecia). This compounded treatment is not approved by the FDA and is only available if prescribed after an online consultation with a licensed physician through the XYON Health platform.

Data from small scale and case studies suggests that taking finasteride in combination with minoxidil may increase the effectiveness of hair loss treatment in some patients. This may be due to different mechanisms of action that help address the various causes of pattern hair loss.


What should I tell my healthcare provider before taking finasteride and minoxidil?

Please inform your doctor or healthcare provider if any of the following apply:

  • You have a personal or family history of prostate cancer, breast cancer
  • You have prostate or urinary symptoms such as reduced urine flow, difficulty urinating or pain
  • You have a history of heart conditions (e.g., high blood pressure, heart failure, previous heart attack, pericarditis, abnormal heart rhythm, chest pain/angina)
  • You have a history of vascular conditions (e.g., stroke, severe lower leg swelling, pulmonary hypertension)
  • You have a history of liver or kidney disease or dysfunction
  • You have a history of any serious mental health conditions
  • You are pregnant, trying to get pregnant, or are breastfeeding

You should be aware that minoxidil has the potential to be toxic to some animals. Please ensure that pets do not come into contact with minoxidil or lick your hands after application.


Who should not take finasteride and minoxidil?

You should not take finasteride and minoxidil if you: 

  • Have ever had an allergic reaction to finasteride, minoxidil or any other ingredients in the treatment
  • Have a history of liver disease or dysfunction
  • Finasteride and minoxidil should not be used by women who are pregnant, may be pregnant or are breastfeeding
  • Finasteride and minoxidil should not be used by infants or children

Black box warning: Serious cardiac effects associated with oral minoxidil

  • Oral minoxidil has a black box warning because the medication is a powerful antihypertensive agent. Serious cardiovascular side effects have been observed in clinical trials where the drug has been used to treat symptomatic high blood pressure. When used off-label for hair loss, oral minoxidil is typically dosed at less than 5mg to help reduce the likelihood of experiencing an adverse cardiovascular event
  • Oral minoxidil can cause pericardial effusion, which can progress to a condition called tamponade which increases pressure on the heart and keeps it from beating properly. This can result in sharp chest pain and difficulty breathing. Seek emergency treatment if this occurs
  • Chest pain warning: Minoxidil can increase your heart rate and cause or worsen chest pain. If you have new or worsening pain in the chest, arm, or shoulders, tell your doctor right away or go to the nearest emergency department.
  • Heart function warning: Minoxidil can cause poor heart function or worsen existing heart problems like heart failure. When tested on animals, minoxidil caused several kinds of lesions of the heart muscle as well as other adverse heart effects. Patients with malignant hypertension and those already receiving guanethidine should be hospitalized when minoxidil is first administered so that they can be monitored to avoid too rapid or large decreases in blood pressure

What are the possible side effects of finasteride and minoxidil?

The following side effects have been reported with finasteride use:

  • Breast tenderness and enlargement. You should inform your doctor or healthcare provider if you notice any breast lumps, pain or nipple discharge
  • Depression, anxiety, brain fog, suicidal ideation
  • Decrease libido (sex drive)
  • Allergic reactions (e.g., rash, itching, hives and swelling of the lips, tongue, throat, and face)
  • Problems with ejaculation
  • Testicular pain
  • Erectile dysfunction (difficulty achieving or maintaining an erection)
  • Male infertility and/or poor semen quality

Please note that finasteride has only been formally studied in male patients, so the side effect profile above is specific to clinical studies in men. Preliminary data on the use of finasteride in female patients has shown the following possible side effects:

  • Decreased libido (sex drive)
  • Breast tenderness and enlargement
  • Mood changes (e.g., depression)
  • Fatigue
  • Muscle soreness
  • Weight gain

There is some evidence that finasteride can increase the risk of some breast and prostate cancers.


When used off label in a topical form, systemic side effects of finasteride and minoxidil are expected to be less frequent/severe. The following is a list of possible side effects associated with the use of topical finasteride:

  • Itching
  • Irritation
  • Dry and flaky scalp
  • Increased scalp oiliness

The following side effects have been reported with topical minoxidil use:

  • Itchy scalp or skin rash
  • Dryness, scaling, or flakiness
  • Redness or irritation at the application site

The above lists do not represent all potential side effects, medication interactions or study data relating to the safety of finasteride and minoxidil. It is important to talk to your doctor, healthcare provider and/or pharmacist if you are experiencing any side effects. A comprehensive review of the potential safety risks of using finasteride and other similar medications can be found at this link: A review of minoxidil, its clinical applications and safety can be found at this link: If you are experiencing a medical emergency or allergic reaction, call 911 or seek immediate medical attention. You are encouraged to report negative side effects of prescription products to the FDA. Visit or call 1-800-FDA-1088. Additional safety information can be found here, in the Digital Prescriber’s Reference for finasteride: and Digital Prescriber’s Reference for oral minoxidil:

* This page was medically reviewed by Dr. Christina Han, MD FRCPC.

* Topical Finasteride and Minoxidil is a compounded medication that is not FDA-approved. Finasteride is not FDA-approved for use in women. Only available if prescribed after an online consultation with a licensed healthcare provider, for off-label use.

US Pat. no. 11,786,466

SiloxysSystem™ Gel

Our unique solution delivers hair loss medication where you need it and not where you don’t. Concentrating ingredients directly at the hair follicles and slowly releasing them over many hours may help reduce how much medication is absorbed into the body and lower the risk of side effects.

The result? A safer, more effective hair loss solution. Only at XYON. 

About SiloxysSystem™ Gel

How topical finasteride and minoxidil treats female hair loss.

Experiencing female pattern hair loss? You’re not alone. It impacts approximately 40% of postmenopausal women. Potential contributors include genetics, hormonal changes and even environmental and lifestyle factors. Our combination treatment helps by:

Illustration by XYON showing how finasteride lowers DHT in women

Stopping Hair Loss

Finasteride lowers levels of the hormone DHT, preventing it from shrinking the hair follicles and causing hair loss.

Illustration by XYON showing how minoxidil promotes hair growth in women

Promoting Hair Growth

Minoxidil increases the flow of blood and nutrients to the scalp and stimulates the active growth phase of the hair cycle.

Illustration showing how combining minoxidil and finasteride increases efficacy

Increasing the Effectiveness

Targeting the cause while also boosting growth, increases chances of success when dealing with complex hair needs.

Does topical finasteride and minoxidil work for women?


reported thicker hair after taking finasteride.

Is topical finasteride and minoxidil safe for women?

SiloxysSystem™ Gel is designed to be a safer way for women to use topical finasteride and minoxidil because it helps reduce the risk of side effects. However, women who are pregnant, trying to become pregnant, or breastfeeding should still avoid taking finasteride. Women who are pregnant or have a history of heart disease should avoid taking minoxidil.

See how SiloxysSystem™ Gel compares.
SiloxysSystem™ Gel

SiloxysSystem™ Gel

Topical Finasteride Sprays & Solutions - XYONHealth

Sprays & Solutions




Mesh technology helps limit amount of medication absorbed into the body.

Difficult to control absorption of ingredients into the body.

Exposes entire body, greater potential for side effects.


Slowly throughout the day to minimize absorption into the bloodstream. 

All at once. May be messy and require multiple daily applications for effectiveness.

Through the bloodstream. Impacts entire body, which may not be needed.

How to use topical finasteride and minoxidil gel.

Make the most of your hair loss treatment.

Take control of your hair health.

Our library of medically-reviewed resources is designed to equip you with the information you need to start your journey with confidence.

A process that prioritizes you.

Hair loss feels personal, so we made our journey to match. 

Accessible Care 

From connecting with physicians to accessing treatment plans, our process is 100% online and designed for convenience.

Custom Treatments

We've partnered with pharmacies that specialize in providing specially made treatments, so you get the care you deserve.

Automated Deliveries

Enjoy peace of mind knowing we'll take care of refilling your prescriptions and making sure they get to your door. 

Have questions? We have answers.

Here are some of the most commonly asked questions about using topical finasteride and minoxidil for female hair loss.