SiloxysSystem™ Gel
Designed to keep topical medications localized to the skin. Used by specialist physicians in clinical practice. Now availible through an online consultation.
17x more active ingredient stays in the scalp versus other topicals
8x less body absorption vs other gels
Compare your options.
What makes it different
Ours keeps medication local. Most topicals absorb fast, which can increase risk of side effects — rushing into your bloodstream instead of staying on your scalp.
17× more retained in the scalp, 92% less in bloodstream vs pills.
How it works
Releases medication gradually over hours instead of dumping it all at once. Our patented technology controls release speed.
Right for you if
You've heard the side-effect stories and want a smarter approach that targets your scalp, not your whole body.
Ours keeps medication local. Most topicals absorb fast, which can increase risk of side effects — rushing into your bloodstream instead of staying on your scalp.
Why people choose this
Enhances delivery into deeper layers of the skin.
Good to know
Standard liposomal gels are good at pushing medication into the skin — sometimes a little too good. Lower concentrations are needed to avoid too much systemic exposure.
SiloxysSystem is engineered for the opposite: releases medication gradually and helps keep more of it in the scalp.
Consider this if
You want a gel formula but aren't concerned about how much gets into your bloodstream.
If systemic absorption worries you, choose SiloxysSystem Gel instead.
Enhances delivery into deeper layers of the skin.
Why people choose this
Quick to apply and dries quickly. Intended for lower body exposure vs. FDA-approved oral medication.
Good to know
Amount of systemic absorption can vary widely between formulas. In some cases, blood levels can be similar to, or even higher than, oral formats.
No verified industry data available on bloodstream absorption rates.
Consider this if
If you need something quick-drying and aren't worried about absorption.
Quick to apply and dries quickly. Intended for lower body exposure vs. FDA-approved oral medication.
Why people choose this
Inexpensive. Simple to add to routine. Suitable for men with a pregnant partner.
Good to know
Oral finasteride is FDA-approved, but its potential for side effects leads some doctors to prescribe topicals instead.
SiloxysSystem Gel achieves 92% less body absorption than oral finasteride.*
Consider this if
If you value convenience-first and tolerate pills well.
Inexpensive. Simple to add to routine. Suitable for men with a pregnant partner.
How XYON is finally solving a 20-year challenge
Effective for hair loss, but it travels through your entire body to reach your follicles. More exposure means a higher potential for side effects.
These compounded formulas absorb through the skin and into the bloodstream rapidly. A new route. The same potential side effect problem.
A patented gel that holds medication at the scalp so more reaches your follicles. Releases slowly to limit absorption into the body, designed to limit side effects.
Select your preferred ingredients. Your physician confirms what's right for you.
SiloxysSystem™ Gel delivers topical finasteride to the scalp as part of a doctor-prescribed hair loss treatment plan, with controlled release - uniquely designed to reduce systemic side effect risk.
Learn moreSiloxysSystem™ Gel delivers topical finasteride and minoxidil to the scalp as part of a doctor-prescribed combination hair loss treatment plan, combining DHT-targeting with follicle stimulation ...
Learn moreSiloxysSystem™ Gel is uniquely designed to deliver topical dutasteride that potently blocks DHT directly to the scalp and keep it there to reduce systemic side effect risk, as part of a docto...
Learn more
SiloxysSystem™ Gel delivers topical finasteride to the scalp as part of a doctor-prescribed hair loss treatment plan, with controlled release - uniquely desi...
Learn more
SiloxysSystem™ Gel delivers topical finasteride and minoxidil to the scalp as part of a doctor-prescribed combination hair loss treatment plan, combining ...
Learn more
SiloxysSystem™ Gel is uniquely designed to deliver topical dutasteride that potently blocks DHT directly to the scalp and keep it there to reduce syste...
Learn moreFounded by a world-renowned hair surgeon and a life sciences CEO with 25 years in drug development.
“Some of my patients couldn’t tolerate oral finasteride. A targeted topical technology didn’t exist yet, so we built it.”
“Our innovation rethought how medication is delivered to the scalp, giving patients worried about side effects another option.”
Share your medical history and select your treatment preference. Upload photos of your hair. Your doctor may ask you to verify your identity through your secure account.
A doctor reviews your consultation and decides on the ideal treatment plan for your needs.
Your medication is fulfilled and shipped by the pharmacy. Most orders ship within one week of fulfillment. — we'll send tracking details once your prescription ships.
Log in anytime to request changes to your plan, medication, or dosage. Changes to your medication or dosage require doctor approval. Have questions? We're here.
The SiloxysSystem gel matrix uses a higher topical concentration because the controlled-release delivery mechanism is designed for it. Despite the higher concentration in the gel, serum (blood) levels are approximately 12× lower than a standard 1mg oral finasteride tablet. The delivery system determines how much reaches the bloodstream — not the concentration in the bottle.
Liquid topical finasteride uses an alcohol or propylene glycol base that evaporates quickly, depositing the medication on the scalp surface. Much of it absorbs systemically or runs off. SiloxysSystem Gel uses a silicone-based matrix that forms a controlled-release lattice — holding medication at the follicle and releasing it gradually over hours.
No. XYON's SiloxysSystem formulations are compounded prescription medications. No FDA-approved topical finasteride currently exists. These formulations were developed to fill a clinical gap for patients and physicians who need an alternative to oral delivery. All prescriptions are based on individual clinical evaluation by a licensed physician.
Yes. All SiloxysSystem Gel treatments are prescription medications. You'll complete a brief online consultation, and a licensed physician will review your medical history and determine if this treatment is appropriate for you.
Many patients use SiloxysSystem Gel alongside other treatments such as oral minoxidil, PRP therapy, or low-level laser therapy. Your prescribing physician can advise on the right combination based on your individual needs.
