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SiloxysSystem™ Gel

Designed to keep topical medications localized to the skin. Used by specialist physicians in clinical practice. Now availible through an online consultation.

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SiloxysSystem™ Gel
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Where your medication goes matters

  • 01

    17x more active ingredient stays in the scalp versus other topicals ¹

  • 02

    8x less body absorption vs other gels ¹

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¹ Based on data on file

Not all delivery methods work the same

Compare your options.

SiloxysSystem™ Gel

Our formula

What makes it different

Ours keeps medication local. Most topicals absorb fast, which can increase risk of side effects — rushing into your bloodstream instead of staying on your scalp.

17× more retained in the scalp, 92% less in bloodstream vs pills.

How it works

Releases medication gradually over hours instead of dumping it all at once. Our patented technology controls release speed.

Right for you if

You've heard the side-effect stories and want a smarter approach that targets your scalp, not your whole body.

Ours keeps medication local. Most topicals absorb fast, which can increase risk of side effects — rushing into your bloodstream instead of staying on your scalp.

Other liposomal gels

Why people choose this

Enhances delivery into deeper layers of the skin.

Good to know

Standard liposomal gels are good at pushing medication into the skin — sometimes a little too good. Lower concentrations are needed to avoid too much systemic exposure.

SiloxysSystem is engineered for the opposite: releases medication gradually and helps keep more of it in the scalp.

Consider this if

You want a gel formula but aren't concerned about how much gets into your bloodstream.

If systemic absorption worries you, choose SiloxysSystem Gel instead.

Enhances delivery into deeper layers of the skin.

Topical spray / solution

Why people choose this

Quick to apply and dries quickly. Intended for lower body exposure vs. FDA-approved oral medication.

Good to know

Amount of systemic absorption can vary widely between formulas. In some cases, blood levels can be similar to, or even higher than, oral formats.

No verified industry data available on bloodstream absorption rates.

Consider this if

If you need something quick-drying and aren't worried about absorption.

Quick to apply and dries quickly. Intended for lower body exposure vs. FDA-approved oral medication.

Oral medications

Why people choose this

Inexpensive. Simple to add to routine. Suitable for men with a pregnant partner.

Good to know

Oral finasteride is FDA-approved, but its potential for side effects leads some doctors to prescribe topicals instead.

SiloxysSystem Gel achieves 92% less body absorption than oral finasteride.*

Consider this if

If you value convenience-first and tolerate pills well.

Inexpensive. Simple to add to routine. Suitable for men with a pregnant partner.

Compounded medicines are not FDA approved and have not been reviewed for safety, efficacy, or quality. Prescription medications require an online consultation with a healthcare provider who will determine if a prescription is appropriate. Restrictions apply.

How XYON is finally solving a 20-year challenge

1997
Oral Finasteride

A pill that works — at a cost.

Effective for hair loss, but it travels through your entire body to reach your follicles. More exposure means a higher potential for side effects.

2010
Other Topical Finasteride

Applied to the scalp — a step forward

These compounded formulas absorb through the skin and into the bloodstream rapidly. A new route. The same potential side effect problem.

Now
XYON SiloxysSystem™ Gel

Engineered to stay exactly where it's needed

A patented gel that holds medication at the scalp so more reaches your follicles. Releases slowly to limit absorption into the body, designed to limit side effects.

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Clinically chosen formulations

Select your preferred ingredients. Your physician confirms what's right for you.

Topical Finasteride with SiloxysSystem™ GelTopical Finasteride & Minoxidil with SiloxysSystem™ GelTopical Dutasteride with SiloxysSystem™ Gel
SiloxysSystem™ Gel

Finasteride Gel

SiloxysSystem™ Gel delivers topical finasteride to the scalp as part of a doctor-prescribed hair loss treatment plan, with controlled release - uniquely designed to reduce systemic side effect risk.

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SiloxysSystem™ Gel

Finasteride & Minoxidil Gel

SiloxysSystem™ Gel delivers topical finasteride and minoxidil to the scalp as part of a doctor-prescribed combination hair loss treatment plan, combining DHT-targeting with follicle stimulation ...

Learn more
SiloxysSystem™ Gel

Dutasteride Gel

SiloxysSystem™ Gel is uniquely designed to deliver topical dutasteride that potently blocks DHT directly to the scalp and keep it there to reduce systemic side effect risk, as part of a docto...

Learn more
SiloxysSystem™ Gel

Finasteride Gel

SiloxysSystem™ Gel delivers topical finasteride to the scalp as part of a doctor-prescribed hair loss treatment plan, with controlled release - uniquely desi...

Learn more
SiloxysSystem™ Gel

Finasteride & Minoxidil Gel

SiloxysSystem™ Gel delivers topical finasteride and minoxidil to the scalp as part of a doctor-prescribed combination hair loss treatment plan, combining ...

Learn more
SiloxysSystem™ Gel

Dutasteride Gel

SiloxysSystem™ Gel is uniquely designed to deliver topical dutasteride that potently blocks DHT directly to the scalp and keep it there to reduce syste...

Learn more

Results from our patients

Baseline Before — J.D.
After After — J.D.
J.D. Started at age 24
Stage
Norwood IIINorwood ScaleThe Norwood scale (or Hamilton-Norwood scale) is the primary classification system used by clinicians to measure the seven stages of male pattern baldness, ranging from minimal loss to severe hair loss. It tracks hairline recession at the temples, crown thinning (vertex), and the merging of these areas to help determine treatment options.Read more →
Moderate
Treatment plan
Topical Dutasteride
“"My experience with XYON's topical Finasteride and Dutasteride has been amazing. The results have boosted my confidence and eased my anxiety about hair loss…”
Baseline Before — G.Y.
After After — G.Y.
G.Y. Started at age 29
Stage
Norwood IIINorwood ScaleThe Norwood scale (or Hamilton-Norwood scale) is the primary classification system used by clinicians to measure the seven stages of male pattern baldness, ranging from minimal loss to severe hair loss. It tracks hairline recession at the temples, crown thinning (vertex), and the merging of these areas to help determine treatment options.Read more →
Moderate
Treatment plan
Topical Dutasteride
“I've been using the treatment for three years now with no side effects, and the results have been life-changing…”
Baseline Before — M.L.
After After — M.L.
M.L. Started at age 37
Stage
Norwood IIINorwood ScaleThe Norwood scale (or Hamilton-Norwood scale) is the primary classification system used by clinicians to measure the seven stages of male pattern baldness, ranging from minimal loss to severe hair loss. It tracks hairline recession at the temples, crown thinning (vertex), and the merging of these areas to help determine treatment options.Read more →
Moderate
Treatment plan
Topical Dutasteride
Baseline Before — S.N.
After After — S.N.
S.N. Started at age 38
Stage
Norwood IVNorwood ScaleThe Norwood scale (or Hamilton-Norwood scale) is the primary classification system used by clinicians to measure the seven stages of male pattern baldness, ranging from minimal loss to severe hair loss. It tracks hairline recession at the temples, crown thinning (vertex), and the merging of these areas to help determine treatment options.Read more →
Moderate
Treatment plan
Topical Dutasteride
Baseline Before — S.B.
After After — S.B.
S.B.
Stage
Norwood IVNorwood ScaleThe Norwood scale (or Hamilton-Norwood scale) is the primary classification system used by clinicians to measure the seven stages of male pattern baldness, ranging from minimal loss to severe hair loss. It tracks hairline recession at the temples, crown thinning (vertex), and the merging of these areas to help determine treatment options.Read more →
Moderate
Treatment plan
Topical Dutasteride
Baseline Before — P.C.
After After — P.C.
P.C. Started at age 53
Stage
Norwood VNorwood ScaleThe Norwood scale (or Hamilton-Norwood scale) is the primary classification system used by clinicians to measure the seven stages of male pattern baldness, ranging from minimal loss to severe hair loss. It tracks hairline recession at the temples, crown thinning (vertex), and the merging of these areas to help determine treatment options.Read more →
Significant
Treatment plan
Topical Dutasteride
“I'm currently using the topical dutasteride and I had noticeable changes in 3 months…”
Baseline Before — A.J.
After After — A.J.
A.J.
Stage
Norwood VaNorwood ScaleThe Norwood scale (or Hamilton-Norwood scale) is the primary classification system used by clinicians to measure the seven stages of male pattern baldness, ranging from minimal loss to severe hair loss. It tracks hairline recession at the temples, crown thinning (vertex), and the merging of these areas to help determine treatment options.Read more →
Treatment plan
Topical Dutasteride
Baseline Before — J.B.
After After — J.B.
J.B. Started at age 33
Stage
Norwood IIINorwood ScaleThe Norwood scale (or Hamilton-Norwood scale) is the primary classification system used by clinicians to measure the seven stages of male pattern baldness, ranging from minimal loss to severe hair loss. It tracks hairline recession at the temples, crown thinning (vertex), and the merging of these areas to help determine treatment options.Read more →
Moderate
Treatment plan
Topical Finasteride + Minoxidil
Baseline Before — JV
After After — JV
JV Started at age 35
Stage
Norwood IVNorwood ScaleThe Norwood scale (or Hamilton-Norwood scale) is the primary classification system used by clinicians to measure the seven stages of male pattern baldness, ranging from minimal loss to severe hair loss. It tracks hairline recession at the temples, crown thinning (vertex), and the merging of these areas to help determine treatment options.Read more →
Moderate
Treatment plan
Topical Finasteride + Minoxidil
“"I've been using XYON's topical finasteride and minoxidil gel for a few months…”
Baseline Before — A.B.
After After — A.B.
A.B. Started at age 35
Stage
Norwood VNorwood ScaleThe Norwood scale (or Hamilton-Norwood scale) is the primary classification system used by clinicians to measure the seven stages of male pattern baldness, ranging from minimal loss to severe hair loss. It tracks hairline recession at the temples, crown thinning (vertex), and the merging of these areas to help determine treatment options.Read more →
Significant
Treatment plan
Topical Finasteride + Minoxidil
“I love the results, obviously. I also like the convenience and ease of managing everything…”
Baseline Before — C.D.
After After — C.D.
C.D.
Stage
Norwood IIINorwood ScaleThe Norwood scale (or Hamilton-Norwood scale) is the primary classification system used by clinicians to measure the seven stages of male pattern baldness, ranging from minimal loss to severe hair loss. It tracks hairline recession at the temples, crown thinning (vertex), and the merging of these areas to help determine treatment options.Read more →
Moderate
Treatment plan
Topical Finasteride
“Seeing my hair stabilize and rebound, especially around my hairline, was exactly what I was hoping for.”
Baseline Before — A.H.
After After — A.H.
A.H.
Stage
Norwood IIINorwood ScaleThe Norwood scale (or Hamilton-Norwood scale) is the primary classification system used by clinicians to measure the seven stages of male pattern baldness, ranging from minimal loss to severe hair loss. It tracks hairline recession at the temples, crown thinning (vertex), and the merging of these areas to help determine treatment options.Read more →
Moderate
Treatment plan
Topical Finasteride
Baseline Before — Nirav P.
After After — Nirav P.
Nirav P.
Stage
Norwood IVNorwood ScaleThe Norwood scale (or Hamilton-Norwood scale) is the primary classification system used by clinicians to measure the seven stages of male pattern baldness, ranging from minimal loss to severe hair loss. It tracks hairline recession at the temples, crown thinning (vertex), and the merging of these areas to help determine treatment options.Read more →
Moderate
Treatment plan
Topical Finasteride
+ Topical Minoxidil 5%
“XYON's Topical Finasteride helped me reverse my hair loss and increase my hair thickness and it's been the game changer I always needed to stop my hair loss.”
Baseline Before — F.P.
After After — F.P.
F.P. Started at age 28
Stage
Norwood VaNorwood ScaleThe Norwood scale (or Hamilton-Norwood scale) is the primary classification system used by clinicians to measure the seven stages of male pattern baldness, ranging from minimal loss to severe hair loss. It tracks hairline recession at the temples, crown thinning (vertex), and the merging of these areas to help determine treatment options.Read more →
Treatment plan
Topical Finasteride
+ Hair Transplant, Oral Minoxidil
“I saw improvements everywhere. It’s difficult to gauge because of my hair transplants, but I know the finasteride from XYON helped my hair, especially the miniaturized hair.”
Baseline Before — V.Y.X.
After After — V.Y.X.
V.Y.X.
Stage
Norwood VINorwood ScaleThe Norwood scale (or Hamilton-Norwood scale) is the primary classification system used by clinicians to measure the seven stages of male pattern baldness, ranging from minimal loss to severe hair loss. It tracks hairline recession at the temples, crown thinning (vertex), and the merging of these areas to help determine treatment options.Read more →
Significant
Treatment plan
Topical Finasteride
Baseline Before — Chris M.
After After — Chris M.
Chris M. Started at age 21
Stage
Norwood VINorwood ScaleThe Norwood scale (or Hamilton-Norwood scale) is the primary classification system used by clinicians to measure the seven stages of male pattern baldness, ranging from minimal loss to severe hair loss. It tracks hairline recession at the temples, crown thinning (vertex), and the merging of these areas to help determine treatment options.Read more →
Significant
Treatment plan
Topical Finasteride
+ Minoxidil + Hair Transplant
“I've seen incredible results with finasteride and minoxidil after 4 months…”
See more results →

Individual results may vary. The case studies and testimonials shown reflect the personal experiences and opinions of the individuals featured. They are not statements or claims by XYON Health and should not be interpreted as guarantees of outcome. Results depend on factors including genetics, adherence, and underlying medical conditions. Always consult a qualified healthcare provider before starting any treatment.

Created in the clinic, not the boardroom.

Founded by a world-renowned hair surgeon and a life sciences CEO with 25 years in drug development.

Dr. Victor Hasson, MD
Co-founder · Lead Surgeon · Hasson & Wong
“Some of my patients couldn’t tolerate oral finasteride. A targeted topical technology didn’t exist yet, so we built it.”
7,500+
hair restoration procedures
30+
years in hair restoration
Dr. Simon Pimstone, MD PhD
Co-founder · CEO · Internal Medicine
“Our innovation rethought how medication is delivered to the scalp, giving patients worried about side effects another option.”
25+
years in pharma
Clinical Professor
University of British Columbia

How XYON works

How XYON works
Complete your consultation

Share your medical history and select your treatment preference. Upload photos of your hair. Your doctor may ask you to verify your identity through your secure account.

~15 minutes
Connect with a doctor

A doctor reviews your consultation and decides on the ideal treatment plan for your needs.

24–48 hours
Start your prescription

Your medication is fulfilled and shipped by the pharmacy. Most orders ship within one week of fulfillment. — we'll send tracking details once your prescription ships.

Free shipping
Ongoing support

Log in anytime to request changes to your plan, medication, or dosage. Changes to your medication or dosage require doctor approval. Have questions? We're here.

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Frequently asked

What does the 2.5% finasteride concentration mean?

The SiloxysSystem gel matrix uses a higher topical concentration because the controlled-release delivery mechanism is designed for it. Despite the higher concentration in the gel, serum (blood) levels are approximately 12× lower than a standard 1mg oral finasteride tablet. The delivery system determines how much reaches the bloodstream — not the concentration in the bottle.

How is this different from liquid topical finasteride?

Liquid topical finasteride uses an alcohol or propylene glycol base that evaporates quickly, depositing the medication on the scalp surface. Much of it absorbs systemically or runs off. SiloxysSystem Gel uses a silicone-based matrix that forms a controlled-release lattice — holding medication at the follicle and releasing it gradually over hours.

Are these treatments FDA-approved?

No. XYON's SiloxysSystem formulations are compounded prescription medications. No FDA-approved topical finasteride currently exists. These formulations were developed to fill a clinical gap for patients and physicians who need an alternative to oral delivery. All prescriptions are based on individual clinical evaluation by a licensed physician.

Do I need a prescription?

Yes. All SiloxysSystem Gel treatments are prescription medications. You'll complete a brief online consultation, and a licensed physician will review your medical history and determine if this treatment is appropriate for you.

Can I use SiloxysSystem Gel with other hair loss treatments?

Many patients use SiloxysSystem Gel alongside other treatments such as oral minoxidil, PRP therapy, or low-level laser therapy. Your prescribing physician can advise on the right combination based on your individual needs.